October 2007
Dementia
Donepezil for the treatment of agitation in Alzheimer's disease.
Howard RJ, Juszczak E, Ballard CG, Bentham P, Brown RG, Bullock R, Burns AS, Holmes C, Jacoby R, Johnson T, Knapp M, Lindesay J,
O'Brien JT, Wilcock G, Katona C, Jones RW, DeCesare J, Rodger M; CALM-AD Trial Group.
N Engl J Med. 2007 Oct 4;357(14):1382-92.
Substance
Topiramate for treating alcohol dependence: a randomized controlled trial.
Johnson BA, Rosenthal N, Capece JA, Wiegand F, Mao L, Beyers K, McKay A, Ait-Daoud N, Anton RF, Ciraulo DA, Kranzler HR, Mann K,
O'Malley SS, Swift RM; Topiramate for Alcoholism Advisory Board; Topiramate for Alcoholism Study Group.
JAMA. 2007 Oct 10;298(14):1641-51.
Schizophrenia
A systematic review of mortality in schizophrenia: is the differential mortality gap worsening over time?
Saha S, Chant D, McGrath J.
Arch Gen Psychiatry. 2007 Oct;64(10):1123-31.
Depression
The Treatment for Adolescents With Depression Study (TADS): Long-term Effectiveness and Safety Outcomes.
The TADS Team.
Arch Gen Psychiatry. 2007 Oct;64(10):1132-1143.
Trauma
Response Variation following Trauma: A Translational Neuroscience Approach to Understanding PTSD.
Yehuda R, Ledoux J.
Neuron. 2007 Oct 4;56(1):19-32.
Neurology
Therapeutic silencing of mutant huntingtin with siRNA attenuates striatal and cortical neuropathology and behavioral deficits.
Difiglia M, Sena-Esteves M, Chase K, Sapp E, Pfister E, Sass M, Yoder J, Reeves P, Pandey RK, Rajeev KG, Manoharan M, Sah DW, Zamore
PD, Aronin N.
Proc Natl Acad Sci U S A. 2007 Oct 16
Biology
Molecular adaptations underlying susceptibility and resistance to social defeat in brain reward regions.
Krishnan V, Han MH, Graham DL, Berton O, Renthal W, Russo SJ, Laplant Q, Graham A, Lutter M, Lagace DC, Ghose S, Reister R, Tannous P,
Green TA, Neve RL, Chakravarty S, Kumar A, Eisch AJ, Self DW, Lee FS, Tamminga CA, Cooper DC, Gershenfeld HK, Nestler EJ.
Cell. 2007 Oct 19;131(2):391-404.
The Conserved microRNA MiR-8 Tunes Atrophin Levels to Prevent Neurodegeneration in Drosophila.
Karres JS, Hilgers V, Carrera I, Treisman J, Cohen SM.
Cell. 2007 Oct 5;131(1):136-45.