November 2006
Developmental
Enhanced anxiety and stress-induced corticosterone release are associated with increased Crh expression in a
mouse model of Rett syndrome.
McGill BE, Bundle SF, Yaylaoglu MB, Carson JP, Thaller C, Zoghbi HY.
Proc Natl Acad Sci U S A. 2006 Nov 28;103(48):18267-18272.
Alzheimer's
100 years and counting: prospects for defeating Alzheimer's disease.
Roberson ED, Mucke L.
Science. 2006 Nov 3;314(5800):781-4.
Schizophrenia
Akt1 deficiency affects neuronal morphology and predisposes to abnormalities in prefrontal cortex functioning.
Lai WS, Xu B, Westphal KG, Paterlini M, Olivier B, Pavlidis P, Karayiorgou M, Gogos JA.
Proc Natl Acad Sci U S A. 2006 Nov 7;103(45):16906-11.
Depression
Depression induces bone loss through stimulation of the sympathetic nervous system.
Yirmiya R, Goshen I, Bajayo A, Kreisel T, Feldman S, Tam J, Trembovler V, Csernus V, Shohami E, Bab I.
Proc Natl Acad Sci U S A. 2006 Nov 7;103(45):16876-81.
Early Onset of Selective Serotonin Reuptake Inhibitor Antidepressant Action: Systematic Review and Meta-analysis.
Taylor MJ, Freemantle N, Geddes JR, Bhagwagar Z.
Arch Gen Psychiatry. 2006 Nov;63(11):1217-23.
Acute and Longer-Term Outcomes in Depressed Outpatients Requiring One or Several Treatment Steps: A STAR*D
Report.
Rush AJ, Trivedi MH, Wisniewski SR, Nierenberg AA, Stewart JW, Warden D, Niederehe G, Thase ME, Lavori PW, Lebowitz BD,
McGrath PJ, Rosenbaum JF, Sackeim HA, Kupfer DJ, Luther J, Fava M.
Am J Psychiatry. 2006 Nov;163(11):1905-17.
Sleep
Sleep deprivation inhibits adult neurogenesis in the hippocampus by elevating glucocorticoids.
Mirescu C, Peters JD, Noiman L, Gould E.
Proc Natl Acad Sci U S A. 2006 Nov 29
Suicide
Prevalence of and risk factors for lifetime suicide attempts among blacks in the United States.
Joe S, Baser RE, Breeden G, Neighbors HW, Jackson JS.
JAMA. 2006 Nov 1;296(17):2112-23.
The relationship between antidepressant prescription rates and rate of early adolescent suicide.
Gibbons RD, Hur K, Bhaumik DK, Mann JJ.
Am J Psychiatry. 2006 Nov;163(11):1898-904.
Psychology
Rethinking the fear circuit: the central nucleus of the amygdala is required for the acquisition, consolidation, and
expression of pavlovian fear conditioning.
Wilensky AE, Schafe GE, Kristensen MP, LeDoux JE.
J Neurosci. 2006 Nov 29;26(48):12387-96.
Relative blindsight in normal observers and the neural correlate of visual consciousness.
Lau HC, Passingham RE.
Proc Natl Acad Sci U S A. 2006 Nov 21
Biology
A signature pattern of stress-responsive microRNAs that can evoke cardiac hypertrophy and heart failure.
van Rooij E, Sutherland LB, Liu N, Williams AH, McAnally J, Gerard RD, Richardson JA, Olson EN.
Proc Natl Acad Sci U S A. 2006 Nov 28;103(48):18255-60.
Genome-wide analysis of Arabidopsis thaliana DNA methylation uncovers an interdependence between methylation
and transcription.
Zilberman D, Gehring M, Tran RK, Ballinger T, Henikoff S.
Nat Genet. 2006 Nov 26
Global variation in copy number in the human genome.
Redon R, Ishikawa S, Fitch KR, Feuk L, Perry GH, Andrews TD, Fiegler H, Shapero MH, Carson AR, Chen W, Cho EK, Dallaire S,
Freeman JL, Gonzalez JR, Gratacos M, Huang J, Kalaitzopoulos D, Komura D, MacDonald JR, Marshall CR, Mei R, Montgomery
L, Nishimura K, Okamura K, Shen F, Somerville MJ, Tchinda J, Valsesia A, Woodwark C, Yang F, Zhang J, Zerjal T, Zhang J,
Armengol L, Conrad DF, Estivill X, Tyler-Smith C, Carter NP, Aburatani H, Lee C, Jones KW, Scherer SW, Hurles ME.
Nature. 2006 Nov 23;444(7118):444-54.
Activation of an oncogenic microRNA cistron by provirus integration.
Wang CL, Wang BB, Bartha G, Li L, Channa N, Klinger M, Killeen N, Wabl M.
Proc Natl Acad Sci U S A. 2006 Nov 22
Integration of new neurons into functional neural networks.
Ramirez-Amaya V, Marrone DF, Gage FH, Worley PF, Barnes CA.
J Neurosci. 2006 Nov 22;26(47):12237-41.
Analysis of the C. elegans Argonaute family reveals that distinct Argonautes act sequentially during RNAi.
Yigit E, Batista PJ, Bei Y, Pang KM, Chen CC, Tolia NH, Joshua-Tor L, Mitani S, Simard MJ, Mello CC.
Cell. 2006 Nov 17;127(4):747-57.
A chromatin-mediated mechanism for specification of conditional transcription factor targets.
Buck MJ, Lieb JD.
Nat Genet. 2006 Nov 12
Lentiviral vectors with a defective integrase allow efficient and sustained transgene expression in vitro and in vivo.
Philippe S, Sarkis C, Barkats M, Mammeri H, Ladroue C, Petit C, Mallet J, Serguera C.
Proc Natl Acad Sci U S A. 2006 Nov 9
Gene transfer in humans using a conditionally replicating lentiviral vector.
Levine BL, Humeau LM, Boyer J, Macgregor RR, Rebello T, Lu X, Binder GK, Slepushkin V, Lemiale F, Mascola JR, Bushman
FD, Dropulic B, June CH.
Proc Natl Acad Sci U S A. 2006 Nov 7
Learning and memory associated with aggression in Drosophila melanogaster.
Yurkovic A, Wang O, Basu AC, Kravitz EA.
Proc Natl Acad Sci U S A. 2006 Nov 6
In vivo enhancer analysis of human conserved non-coding sequences.
Pennacchio LA, Ahituv N, Moses AM, Prabhakar S, Nobrega MA, Shoukry M, Minovitsky S, Dubchak I, Holt A, Lewis KD,
Plajzer-Frick I, Akiyama J, De Val S, Afzal V, Black BL, Couronne O, Eisen MB, Visel A, Rubin EM.
Nature. 2006 Nov 5
Accelerated evolution of conserved noncoding sequences in humans.
Prabhakar S, Noonan JP, Paabo S, Rubin EM.
Science. 2006 Nov 3;314(5800):786.