Mechanism

CRM1 mediates nuclear-cytoplasmic shuttling of mature microRNAs.
Castanotto D, Lingeman R, Riggs AD, Rossi JJ.
Proc Natl Acad Sci U S A. 2009 Dec 22;106(51):21655-9.

ADARs have effects beyond RNA editing.
Heale BS, Keegan LP, O'Connell MA.
Cell Cycle. 2009 Dec 15;8(24):4011-2.

Marsupial-specific microRNAs evolved from marsupial-specific transposable elements.
Devor EJ, Peek AS, Lanier W, Samollow PB.
Gene. 2009 Dec 15;448(2):187-91.

RNA-binding motif protein 4 translocates to cytoplasmic granules and suppresses translation via argonaute2 during muscle cell
differentiation.
Lin JC, Tarn WY.
J Biol Chem. 2009 Dec 11;284(50):34658-65.

MicroRNA mir-346 targets the 5'-untranslated region of receptor-interacting protein 140 (RIP140) mRNA and up-regulates its protein
expression.
Tsai NP, Lin YL, Wei LN.
Biochem J. 2009 Dec 10;424(3):411-8.

miRNA processing turned upside down.
Schwab R, Voinnet O.
EMBO J. 2009 Dec 2;28(23):3633-4.

A brief review on the mechanisms of miRNA regulation.
Cai Y, Yu X, Hu S, Yu J.
Genomics Proteomics Bioinformatics. 2009 Dec;7(4):147-54.

Mechanisms of microRNA-mediated gene regulation.
Zhao S, Liu MF.
Sci China C Life Sci. 2009 Dec;52(12):1111-6.

Profiling of molecular pathways regulated by microRNA 601.
Ohdaira H, Nakagawa H, Yoshida K.
Comput Biol Chem. 2009 Dec;33(6):429-33.

Novel functions for small RNA molecules.
Zhang C.
Curr Opin Mol Ther. 2009 Dec;11(6):641-51.

Expanded RNA-binding activities of mammalian Argonaute 2.
Tan GS, Garchow BG, Liu X, Yeung J, Morris JP 4th, Cuellar TL, McManus MT, Kiriakidou M.
Nucleic Acids Res. 2009 Dec;37(22):7533-45.

Distinct passenger strand and mRNA cleavage activities of human Argonaute proteins.
Wang B, Li S, Qi HH, Chowdhury D, Shi Y, Novina CD.
Nat Struct Mol Biol. 2009 Dec;16(12):1259-66.

The silencing domain of GW182 interacts with PABPC1 to promote translational repression and degradation of microRNA targets and is
required for target release.
Zekri L, Huntzinger E, Heimstädt S, Izaurralde E.
Mol Cell Biol. 2009 Dec;29(23):6220-31.

Characterization of viral and human RNAs smaller than canonical MicroRNAs.
Li Z, Kim SW, Lin Y, Moore PS, Chang Y, John B.
J Virol. 2009 Dec;83(24):12751-8.

Filtering of deep sequencing data reveals the existence of abundant Dicer-dependent small RNAs derived from tRNAs.
Cole C, Sobala A, Lu C, Thatcher SR, Bowman A, Brown JW, Green PJ, Barton GJ, Hutvagner G.
RNA. 2009 Dec;15(12):2147-60.

Alu-directed transcriptional regulation of some novel miRNAs.
Gu TJ, Yi X, Zhao XW, Zhao Y, Yin JQ.
BMC Genomics. 2009 Nov 30;10:563.

Cell biology. Nuclear export of small RNAs.
Stewart M.
Science. 2009 Nov 27;326(5957):1195-6.

A high-resolution structure of the pre-microRNA nuclear export machinery.
Okada C, Yamashita E, Lee SJ, Shibata S, Katahira J, Nakagawa A, Yoneda Y, Tsukihara T.
Science. 2009 Nov 27;326(5957):1275-9.

A novel class of small RNAs: tRNA-derived RNA fragments (tRFs).
Lee YS, Shibata Y, Malhotra A, Dutta A.
Genes Dev. 2009 Nov 15;23(22):2639-49.

Distinct mechanisms for microRNA strand selection by Drosophila Argonautes.
Okamura K, Liu N, Lai EC.
Mol Cell. 2009 Nov 13;36(3):431-44.

Hierarchical rules for Argonaute loading in Drosophila.
Czech B, Zhou R, Erlich Y, Brennecke J, Binari R, Villalta C, Gordon A, Perrimon N, Hannon GJ.
Mol Cell. 2009 Nov 13;36(3):445-56.

How to control miRNA maturation?
Trabucchi M, Briata P, Filipowicz W, Rosenfeld MG, Ramos A, Gherzi R.
RNA Biol. 2009 Nov-Dec;6(5):536-40.

Dynamics of microRNA-mediated motifs.
Xu F, Liu Z, Shen J, Wang R.
IET Syst Biol. 2009 Nov;3(6):496-504.

Concordant regulation of translation and mRNA abundance for hundreds of targets of a human microRNA.
Hendrickson DG, Hogan DJ, McCullough HL, Myers JW, Herschlag D, Ferrell JE, Brown PO.
PLoS Biol. 2009 Nov;7(11):e1000238.

Comparative assessment of siRNA and shRNA off target effects: what is slowing clinical development.
Rao DD, Senzer N, Cleary MA, Nemunaitis J.
Cancer Gene Ther. 2009 Nov;16(11):807-9.

Relative contribution of sequence and structure features to the mRNA binding of Argonaute/EIF2C-miRNA complexes and the degradation
of miRNA targets.
Hausser J, Landthaler M, Jaskiewicz L, Gaidatzis D, Zavolan M.
Genome Res. 2009 Nov;19(11):2009-20.

Human UPF1 participates in small RNA-induced mRNA downregulation.
Jin H, Suh MR, Han J, Yeom KH, Lee Y, Heo I, Ha M, Hyun S, Kim VN.
Mol Cell Biol. 2009 Nov;29(21):5789-99.

Structural insights into RNA processing by the human RISC-loading complex.
Wang HW, Noland C, Siridechadilok B, Taylor DW, Ma E, Felderer K, Doudna JA, Nogales E.
Nat Struct Mol Biol. 2009 Nov;16(11):1148-53.

Ago-TNRC6 triggers microRNA-mediated decay by promoting two deadenylation steps.
Chen CY, Zheng D, Xia Z, Shyu AB.
Nat Struct Mol Biol. 2009 Nov;16(11):1160-6.

Alternative processing of primary microRNA transcripts by Drosha generates 5' end variation of mature microRNA.
Wu H, Ye C, Ramirez D, Manjunath N.
PLoS One. 2009 Oct 27;4(10):e7566.

Increased MKK4 abundance with replicative senescence is linked to the joint reduction of multiple microRNAs.
Marasa BS, Srikantan S, Masuda K, Abdelmohsen K, Kuwano Y, Yang X, Martindale JL, Rinker-Schaeffer CW, Gorospe M.
Sci Signal. 2009 Oct 27;2(94):ra69.

Hormonal regulation of microRNA biogenesis.
Macias S, Michlewski G, Cáceres JF.
Mol Cell. 2009 Oct 23;36(2):172-3.

Maturation of microRNA is hormonally regulated by a nuclear receptor.
Yamagata K, Fujiyama S, Ito S, Ueda T, Murata T, Naitou M, Takeyama K, Minami Y, O'Malley BW, Kato S.
Mol Cell. 2009 Oct 23;36(2):340-7.

Editing independent effects of ADARs on the miRNA/siRNA pathways.
Heale BS, Keegan LP, McGurk L, Michlewski G, Brindle J, Stanton CM, Caceres JF, O'Connell MA.
EMBO J. 2009 Oct 21;28(20):3145-56.

Divergent intracellular pathways regulate interleukin-1beta-induced miR-146a and miR-146b expression and chemokine release in human
alveolar epithelial cells.
Perry MM, Williams AE, Tsitsiou E, Larner-Svensson HM, Lindsay MA.
FEBS Lett. 2009 Oct 20;583(20):3349-55.

DAZL relieves miRNA-mediated repression of germline mRNAs by controlling poly(A) tail length in zebrafish.
Takeda Y, Mishima Y, Fujiwara T, Sakamoto H, Inoue K.
PLoS One. 2009 Oct 19;4(10):e7513.

Lesser known relatives of miRNA.
Choudhuri S.
Biochem Biophys Res Commun. 2009 Oct 16;388(2):177-80.

Transcription of the C. elegans let-7 microRNA is temporally regulated by one of its targets, hbl-1.
Roush SF, Slack FJ.
Dev Biol. 2009 Oct 15;334(2):523-34.

Human cytosolic tRNase ZL can downregulate gene expression through miRNA.
Elbarbary RA, Takaku H, Uchiumi N, Tamiya H, Abe M, Nishida H, Nashimoto M.
FEBS Lett. 2009 Oct 6;583(19):3241-6.

Phosphorylation of the human microRNA-generating complex mediates MAPK/Erk signaling.
Paroo Z, Ye X, Chen S, Liu Q.
Cell. 2009 Oct 2;139(1):112-22.

Ribosomal protein RPS-14 modulates let-7 microRNA function in Caenorhabditis elegans.
Chan SP, Slack FJ.
Dev Biol. 2009 Oct 1;334(1):152-60.

Control of microRNA biogenesis by TGFbeta signaling pathway-A novel role of Smads in the nucleus.
Hata A, Davis BN.
Cytokine Growth Factor Rev. 2009 Oct-Dec;20(5-6):517-21.

Bioinformatic analysis of microRNA biogenesis and function related proteins in eleven animal genomes.
Liu X, Luo G, Bai X, Wang XJ.
J Genet Genomics. 2009 Oct;36(10):591-601.

[Diversity and complexity of dicer dependent small RNA networks in animals]
Okamura K, Lai EC.
Seikagaku. 2009 Oct;81(10):904-9.

Human villous trophoblasts express and secrete placenta-specific microRNAs into maternal circulation via exosomes.
Luo SS, Ishibashi O, Ishikawa G, Ishikawa T, Katayama A, Mishima T, Takizawa T, Shigihara T, Goto T, Izumi A, Ohkuchi A, Matsubara S,
Takeshita T, Takizawa T.
Biol Reprod. 2009 Oct;81(4):717-29.

Combinatorial network of primary and secondary microRNA-driven regulatory mechanisms.
Tu K, Yu H, Hua YJ, Li YY, Liu L, Xie L, Li YX.
Nucleic Acids Res. 2009 Oct;37(18):5969-80.

Chromatin poises miRNA- and protein-coding genes for expression.
Barski A, Jothi R, Cuddapah S, Cui K, Roh TY, Schones DE, Zhao K.
Genome Res. 2009 Oct;19(10):1742-51.

Coupled RNA processing and transcription of intergenic primary microRNAs.
Ballarino M, Pagano F, Girardi E, Morlando M, Cacchiarelli D, Marchioni M, Proudfoot NJ, Bozzoni I.
Mol Cell Biol. 2009 Oct;29(20):5632-8.

LIN-28 and the poly(U) polymerase PUP-2 regulate let-7 microRNA processing in Caenorhabditis elegans.
Lehrbach NJ, Armisen J, Lightfoot HL, Murfitt KJ, Bugaut A, Balasubramanian S, Miska EA.
Nat Struct Mol Biol. 2009 Oct;16(10):1016-20.

Lin28 recruits the TUTase Zcchc11 to inhibit let-7 maturation in mouse embryonic stem cells.
Hagan JP, Piskounova E, Gregory RI.
Nat Struct Mol Biol. 2009 Oct;16(10):1021-5.

Active turnover modulates mature microRNA activity in Caenorhabditis elegans.
Chatterjee S, Grosshans H.
Nature. 2009 Sep 24;461(7263):546-9.

Mammalian miRNA RISC recruits CAF1 and PABP to affect PABP-dependent deadenylation.
Fabian MR, Mathonnet G, Sundermeier T, Mathys H, Zipprich JT, Svitkin YV, Rivas F, Jinek M, Wohlschlegel J, Doudna JA, Chen CY, Shyu
AB, Yates JR 3rd, Hannon GJ, Filipowicz W, Duchaine TF, Sonenberg N.
Mol Cell. 2009 Sep 24;35(6):868-80.

The chicken or the egg: microRNA-mediated regulation of mRNA translation or mRNA stability.
Omer AD, Janas MM, Novina CD.
Mol Cell. 2009 Sep 24;35(6):739-40.

Drosophila miR2 primarily targets the m7GpppN cap structure for translational repression.
Zdanowicz A, Thermann R, Kowalska J, Jemielity J, Duncan K, Preiss T, Darzynkiewicz E, Hentze MW.
Mol Cell. 2009 Sep 24;35(6):881-8.

Evidence for human microRNA-offset RNAs in small RNA sequencing data.
Langenberger D, Bermudez-Santana C, Hertel J, Hoffmann S, Khaitovich P, Stadler PF.
Bioinformatics. 2009 Sep 15;25(18):2298-301.

Dynamics of the recovery from sRNA-mediated gene silencing.
Semsey S, Benjamin JA, Mitarai N, Krishna S, Csiszovszki Z, Sneppen K, Massé E.
Cell Cycle. 2009 Sep 15;8(18):2863-4.

The estrogen receptor-alpha-induced microRNA signature regulates itself and its transcriptional response.
Castellano L, Giamas G, Jacob J, Coombes RC, Lucchesi W, Thiruchelvam P, Barton G, Jiao LR, Wait R, Waxman J, Hannon GJ,
Stebbing J.
Proc Natl Acad Sci U S A. 2009 Sep 15;106(37):15732-7.

Genomic analysis suggests that mRNA destabilization by the microprocessor is specialized for the auto-regulation of Dgcr8.
Shenoy A, Blelloch R.
PLoS One. 2009 Sep 11;4(9):e6971.

miR-24 Inhibits cell proliferation by targeting E2F2, MYC, and other cell-cycle genes via binding to "seedless" 3'UTR microRNA recognition
elements.
Lal A, Navarro F, Maher CA, Maliszewski LE, Yan N, O'Day E, Chowdhury D, Dykxhoorn DM, Tsai P, Hofmann O, Becker KG, Gorospe M,
Hide W, Lieberman J.
Mol Cell. 2009 Sep 11;35(5):610-25.

Sequence features associated with microRNA strand selection in humans and flies.
Hu HY, Yan Z, Xu Y, Hu H, Menzel C, Zhou YH, Chen W, Khaitovich P.
BMC Genomics. 2009 Sep 4;10:413.

Nuclear receptor SHP activates miR-206 expression via a cascade dual inhibitory mechanism.
Song G, Wang L.
PLoS One. 2009 Sep 1;4(9):e6880.

Caught at its own game: regulatory small RNA inactivated by an inducible transcript mimicking its target.
Figueroa-Bossi N, Valentini M, Malleret L, Bossi L.
Genes Dev. 2009 Sep 1;23(17):2004-15.

Sequence, biogenesis, and function of diverse small RNA classes bound to the Piwi family proteins of Tetrahymena thermophila.
Couvillion MT, Lee SR, Hogstad B, Malone CD, Tonkin LA, Sachidanandam R, Hannon GJ, Collins K.
Genes Dev. 2009 Sep 1;23(17):2016-32.

Regulating the regulator: an RNA decoy acts as an OFF switch for the regulation of an sRNA.
Mandin P, Gottesman S.
Genes Dev. 2009 Sep 1;23(17):1981-5.

Trafficking of mature miRNA-122 into the nucleus of live liver cells.
Földes-Papp Z, König K, Studier H, Bückle R, Breunig HG, Uchugonova A, Kostner GM.
Curr Pharm Biotechnol. 2009 Sep;10(6):569-78.

Human miRNA precursors with box H/ACA snoRNA features.
Scott MS, Avolio F, Ono M, Lamond AI, Barton GJ.
PLoS Comput Biol. 2009 Sep;5(9):e1000507.

Incomplete penetrance and variable expressivity: is there a microRNA connection?
Ahluwalia JK, Hariharan M, Bargaje R, Pillai B, Brahmachari V.
Bioessays. 2009 Sep;31(9):981-92.

Silencing by small RNAs is linked to endosomal trafficking.
Lee YS, Pressman S, Andress AP, Kim K, White JL, Cassidy JJ, Li X, Lubell K, Lim do H, Cho IS, Nakahara K, Preall JB, Bellare P,
Sontheimer EJ, Carthew RW.
Nat Cell Biol. 2009 Sep;11(9):1150-6.

Multivesicular bodies associate with components of miRNA effector complexes and modulate miRNA activity.
Gibbings DJ, Ciaudo C, Erhardt M, Voinnet O.
Nat Cell Biol. 2009 Sep;11(9):1143-9.

Structural determinants of miRNAs for RISC loading and slicer-independent unwinding.
Kawamata T, Seitz H, Tomari Y.
Nat Struct Mol Biol. 2009 Sep;16(9):953-60.

Small RNAs: p53 makes microRNAs mature.
Wrighton KH.
Nat Rev Cancer. 2009 Sep;9(9):612.

RISC hitches onto endosome trafficking.
Siomi H, Siomi MC.
Nat Cell Biol. 2009 Sep;11(9):1049-51.

Widespread cleavage of A-to-I hyperediting substrates.
Osenberg S, Dominissini D, Rechavi G, Eisenberg E.
RNA. 2009 Sep;15(9):1632-9.

MicroRNAs with a nucleolar location.
Politz JC, Hogan EM, Pederson T.
RNA. 2009 Sep;15(9):1705-15.

microRNA-mediated messenger RNA deadenylation contributes to translational repression in mammalian cells.
Beilharz TH, Humphreys DT, Clancy JL, Thermann R, Martin DI, Hentze MW, Preiss T.
PLoS One. 2009 Aug 27;4(8):e6783.

TUT4 in concert with Lin28 suppresses microRNA biogenesis through pre-microRNA uridylation.
Heo I, Joo C, Kim YK, Ha M, Yoon MJ, Cho J, Yeom KH, Han J, Kim VN.
Cell. 2009 Aug 21;138(4):696-708.

miRNA regulation through ligand occupancy of a nuclear hormone receptor.
Rougvie AE.
Sci Signal. 2009 Aug 18;2(84):pe52.

MicroRNA-regulated feed forward loop network.
Cohen EE, Rosner MR.
Cell Cycle. 2009 Aug 15;8(16):2477-8.

Cell contact-dependent acquisition of cellular and viral nonautonomously encoded small RNAs.
Rechavi O, Erlich Y, Amram H, Flomenblit L, Karginov FV, Goldstein I, Hannon GJ, Kloog Y.
Genes Dev. 2009 Aug 15;23(16):1971-9.

Large-scale genome analysis reveals unique features of microRNAs.
Zhang B, Stellwag EJ, Pan X.
Gene. 2009 Aug 15;443(1-2):100-9.

The 5' terminal uracil of let-7a is critical for the recruitment of mRNA to Argonaute2.
Felice KM, Salzman DW, Shubert-Coleman J, Jensen KP, Furneaux HM.
Biochem J. 2009 Aug 13;422(2):329-41.

Large-scale information entropy analysis of important sites in mature and precursor miRNA sequences.
Du J, Wu Y, Zhang Y, Wu L, Wang X, Tao S.
Sci China C Life Sci. 2009 Aug;52(8):771-9.

Genetic modifiers of dFMR1 encode RNA granule components in Drosophila.
Cziko AM, McCann CT, Howlett IC, Barbee SA, Duncan RP, Luedemann R, Zarnescu D, Zinsmaier KE, Parker RR, Ramaswami M.
Genetics. 2009 Aug;182(4):1051-60.

First step in pre-miRNAs processing by human Dicer.
Flores-Jasso CF, Arenas-Huertero C, Reyes JL, Contreras-Cubas C, Covarrubias A, Vaca L.
Acta Pharmacol Sin. 2009 Aug;30(8):1177-85.

Functional dissection of the human TNRC6 (GW182-related) family of proteins.
Baillat D, Shiekhattar R.
Mol Cell Biol. 2009 Aug;29(15):4144-55.

Genome-wide survey of microRNA-transcription factor feed-forward regulatory circuits in human.
Re A, Corá D, Taverna D, Caselle M.
Mol Biosyst. 2009 Aug;5(8):854-67.

The GW182 protein family in animal cells: new insights into domains required for miRNA-mediated gene silencing.
Eulalio A, Tritschler F, Izaurralde E.
RNA. 2009 Aug;15(8):1433-42.

MicroRNAs cross the line: the battle for mRNA stability enters the coding sequence.
Nielsen AF, Gloggnitzer J, Martinez J.
Mol Cell. 2009 Jul 31;35(2):139-40.

CRD-BP protects the coding region of betaTrCP1 mRNA from miR-183-mediated degradation.
Elcheva I, Goswami S, Noubissi FK, Spiegelman VS.
Mol Cell. 2009 Jul 31;35(2):240-6.

AGO1 homeostasis involves differential production of 21-nt and 22-nt miR168 species by MIR168a and MIR168b.
Vaucheret H.
PLoS One. 2009 Jul 30;4(7):e6442.

Ars2 links the nuclear cap-binding complex to RNA interference and cell proliferation.
Gruber JJ, Zatechka DS, Sabin LR, Yong J, Lum JJ, Kong M, Zong WX, Zhang Z, Lau CK, Rawlings J, Cherry S, Ihle JN, Dreyfuss G,
Thompson CB.
Cell. 2009 Jul 23;138(2):328-39.

Ars2 regulates both miRNA- and siRNA- dependent silencing and suppresses RNA virus infection in Drosophila.
Sabin LR, Zhou R, Gruber JJ, Lukinova N, Bambina S, Berman A, Lau CK, Thompson CB, Cherry S.
Cell. 2009 Jul 23;138(2):340-51.

Predicting potential miRNA target sites within gene promoters.
Younger ST, Pertsemlidis A, Corey DR.
Bioorg Med Chem Lett. 2009 Jul 15;19(14):3791-4.

Argonaute-mediated translational repression (and activation).
Iwasaki S, Tomari Y.
Fly (Austin). 2009 Jul-Sep;3(3):204-6.

Non-coding RNAs, epigenetic memory and the passage of information to progeny.
Morris KV.
RNA Biol. 2009 Jul;6(3):242-7.

Hsp90 regulates the function of argonaute 2 and its recruitment to stress granules and P-bodies.
Pare JM, Tahbaz N, López-Orozco J, LaPointe P, Lasko P, Hobman TC.
Mol Biol Cell. 2009 Jul;20(14):3273-84.

New class of microRNA targets containing simultaneous 5'-UTR and 3'-UTR interaction sites.
Lee I, Ajay SS, Yook JI, Kim HS, Hong SH, Kim NH, Dhanasekaran SM, Chinnaiyan AM, Athey BD.
Genome Res. 2009 Jul;19(7):1175-83.

[Regulation of the miRNA function by RNA editing]
Kawahara Y, Nishikura K.
Tanpakushitsu Kakusan Koso. 2009 Jul;54(9):1133-40.

Variation of gene silencing involving endogenous microRNA in mammalian cells.
Tamura Y, Yoshida M, Ohnishi Y, Hohjoh H.
Mol Biol Rep. 2009 Jul;36(6):1413-20.

The NF90-NF45 complex functions as a negative regulator in the microRNA processing pathway.
Sakamoto S, Aoki K, Higuchi T, Todaka H, Morisawa K, Tamaki N, Hatano E, Fukushima A, Taniguchi T, Agata Y.
Mol Cell Biol. 2009 Jul;29(13):3754-69.

Characterization of the miRNA-RISC loading complex and miRNA-RISC formed in the Drosophila miRNA pathway.
Miyoshi K, Okada TN, Siomi H, Siomi MC.
RNA. 2009 Jul;15(7):1282-91.

Dicer independent small RNAs associate with telomeric heterochromatin.
Cao F, Li X, Hiew S, Brady H, Liu Y, Dou Y.
RNA. 2009 Jul;15(7):1274-81.

Small RNAs derived from snoRNAs.
Taft RJ, Glazov EA, Lassmann T, Hayashizaki Y, Carninci P, Mattick JS.
RNA. 2009 Jul;15(7):1233-40.

Clustered microRNAs' coordination in regulating protein-protein interaction network.
Yuan X, Liu C, Yang P, He S, Liao Q, Kang S, Zhao Y.
BMC Syst Biol. 2009 Jun 26;3:65.

The RNA-binding protein KSRP promotes the biogenesis of a subset of microRNAs.
Trabucchi M, Briata P, Garcia-Mayoral M, Haase AD, Filipowicz W, Ramos A, Gherzi R, Rosenfeld MG.
Nature. 2009 Jun 18;459(7249):1010-4.

Functional association of the Microprocessor complex with the spliceosome.
Kataoka N, Fujita M, Ohno M.
Mol Cell Biol. 2009 Jun;29(12):3243-54.

Mechanisms of miRNA-mediated post-transcriptional regulation in animal cells.
Chekulaeva M, Filipowicz W.
Curr Opin Cell Biol. 2009 Jun;21(3):452-60.

Exosomes: proteomic insights and diagnostic potential.
Simpson RJ, Lim JW, Moritz RL, Mathivanan S.
Expert Rev Proteomics. 2009 Jun;6(3):267-83.

Global prediction of tissue-specific gene expression and context-dependent gene networks in Caenorhabditis elegans.
Chikina MD, Huttenhower C, Murphy CT, Troyanskaya OG.
PLoS Comput Biol. 2009 Jun;5(6):e1000417.

Post-transcriptional control of DGCR8 expression by the Microprocessor.
Triboulet R, Chang HM, Lapierre RJ, Gregory RI.
RNA. 2009 Jun;15(6):1005-11.

The C-terminal domains of human TNRC6A, TNRC6B, and TNRC6C silence bound transcripts independently of Argonaute proteins.
Lazzaretti D, Tournier I, Izaurralde E.
RNA. 2009 Jun;15(6):1059-66.

A C-terminal silencing domain in GW182 is essential for miRNA function.
Eulalio A, Helms S, Fritzsch C, Fauser M, Izaurralde E.
RNA. 2009 Jun;15(6):1067-77.

Mammalian GW182 contains multiple Argonaute-binding sites and functions in microRNA-mediated translational repression.
Takimoto K, Wakiyama M, Yokoyama S.
RNA. 2009 Jun;15(6):1078-89.

Abrogation of DNA vector-based RNAi during apoptosis in mammalian cells due to caspase-mediated cleavage and inactivation of
Dicer-1.
Ghodgaonkar MM, Shah RG, Kandan-Kulangara F, Affar EB, Qi HH, Wiemer E, Shah GM.
Cell Death Differ. 2009 Jun;16(6):858-68.

C19MC microRNAs are processed from introns of large Pol-II, non-protein-coding transcripts.
Bortolin-Cavaillé ML, Dance M, Weber M, Cavaillé J.
Nucleic Acids Res. 2009 Jun;37(10):3464-73.

Analyzing miRNA co-expression networks to explore TF-miRNA regulation.
Bandyopadhyay S, Bhattacharyya M.
BMC Bioinformatics. 2009 May 28;10:163.

Bone morphogenetic protein-2 down-regulates miR-206 expression by blocking its maturation process.
Sato MM, Nashimoto M, Katagiri T, Yawaka Y, Tamura M.
Biochem Biophys Res Commun. 2009 May 22;383(1):125-9.

miRNA-regulated dynamics in circadian oscillator models.
Nandi A, Vaz C, Bhattacharya A, Ramaswamy R.
BMC Syst Biol. 2009 May 5;3:45.

The RRM domain in GW182 proteins contributes to miRNA-mediated gene silencing.
Eulalio A, Tritschler F, Büttner R, Weichenrieder O, Izaurralde E, Truffault V.
Nucleic Acids Res. 2009 May;37(9):2974-83.

Meta-analysis of small RNA-sequencing errors reveals ubiquitous post-transcriptional RNA modifications.
Ebhardt HA, Tsang HH, Dai DC, Liu Y, Bostan B, Fahlman RP.
Nucleic Acids Res. 2009 May;37(8):2461-70.

ARGONAUTE 1 homeostasis invokes the coordinate action of the microRNA and siRNA pathways.
Mallory AC, Vaucheret H.
EMBO Rep. 2009 May;10(5):521-6.

Arginine methylation of Piwi proteins catalysed by dPRMT5 is required for Ago3 and Aub stability.
Kirino Y, Kim N, de Planell-Saguer M, Khandros E, Chiorean S, Klein PS, Rigoutsos I, Jongens TA, Mourelatos Z.
Nat Cell Biol. 2009 May;11(5):652-8.

An expanded seed sequence definition accounts for full regulation of the hid 3' UTR by bantam miRNA.
Nahvi A, Shoemaker CJ, Green R.
RNA. 2009 May;15(5):814-22.

Multiple independent domains of dGW182 function in miRNA-mediated repression in Drosophila.
Chekulaeva M, Filipowicz W, Parker R.
RNA. 2009 May;15(5):794-803.

Importance of the C-terminal domain of the human GW182 protein TNRC6C for translational repression.
Zipprich JT, Bhattacharyya S, Mathys H, Filipowicz W.
RNA. 2009 May;15(5):781-93.

Tdrd6 is required for spermiogenesis, chromatoid body architecture, and regulation of miRNA expression.
Vasileva A, Tiedau D, Firooznia A, Müller-Reichert T, Jessberger R.
Curr Biol. 2009 Apr 28;19(8):630-9.

Cell-cell contact globally activates microRNA biogenesis.
Hwang HW, Wentzel EA, Mendell JT.
Proc Natl Acad Sci U S A. 2009 Apr 28;106(17):7016-21.

New tricks for animal microRNAS: targeting of amino acid coding regions at conserved and nonconserved sites.
Rigoutsos I.
Cancer Res. 2009 Apr 15;69(8):3245-8.

Human microRNAs co-silence in well-separated groups and have different predicted essentialities.
Boross G, Orosz K, Farkas IJ.
Bioinformatics. 2009 Apr 15;25(8):1063-9.

Microtranscriptome regulation by gonadotropin-releasing hormone.
Yuen T, Ruf F, Chu T, Sealfon SC.
Mol Cell Endocrinol. 2009 Apr 10;302(1):12-7.

Prediction of guide strand of microRNAs from its sequence and secondary structure.
Ahmed F, Ansari HR, Raghava GP.
BMC Bioinformatics. 2009 Apr 9;10:105.

Translation regulation of mRNAs by the fragile X family of proteins through the microRNA pathway.
Cheever A, Ceman S.
RNA Biol. 2009 Apr-Jun;6(2):175-8.

The interplay between transcription factors and microRNAs in genome-scale regulatory networks.
Martinez NJ, Walhout AJ.
Bioessays. 2009 Apr;31(4):435-45.

A study of microRNAs in silico and in vivo: bioimaging of microRNA biogenesis and regulation.
Kim S, Hwang do W, Lee DS.
FEBS J. 2009 Apr;276(8):2165-74.

Many X-linked microRNAs escape meiotic sex chromosome inactivation.
Song R, Ro S, Michaels JD, Park C, McCarrey JR, Yan W.
Nat Genet. 2009 Apr;41(4):488-93.

Allegro: analyzing expression and sequence in concert to discover regulatory programs.
Halperin Y, Linhart C, Ulitsky I, Shamir R.
Nucleic Acids Res. 2009 Apr;37(5):1566-79.

Functional links between clustered microRNAs: suppression of cell-cycle inhibitors by microRNA clusters in gastric cancer.
Kim YK, Yu J, Han TS, Park SY, Namkoong B, Kim DH, Hur K, Yoo MW, Lee HJ, Yang HK, Kim VN.
Nucleic Acids Res. 2009 Apr;37(5):1672-81.

Congruent evolution of genetic and environmental robustness in micro-RNA.
Szöllosi GJ, Derényi I.
Mol Biol Evol. 2009 Apr;26(4):867-74.

Genome-wide identification of targets of the drosha-pasha/DGCR8 complex.
Kadener S, Rodriguez J, Abruzzi KC, Khodor YL, Sugino K, Marr MT 2nd, Nelson S, Rosbash M.
RNA. 2009 Apr;15(4):537-45.

Regulation of microRNA expression by HMGA1 proteins.
De Martino I, Visone R, Fedele M, Petrocca F, Palmieri D, M Hoyos J, Forzati F, Croce CM, Fusco A.
Oncogene. 2009 Mar 19;28(11):1432-42.

TRIM-NHL proteins take on miRNA regulation.
Loedige I, Filipowicz W.
Cell. 2009 Mar 6;136(5):818-20.

nhl-2 Modulates microRNA activity in Caenorhabditis elegans.
Hammell CM, Lubin I, Boag PR, Blackwell TK, Ambros V.
Cell. 2009 Mar 6;136(5):926-38.

Control of Dead end localization and activity--implications for the function of the protein in antagonizing miRNA function.
Slanchev K, Stebler J, Goudarzi M, Cojocaru V, Weidinger G, Raz E.
Mech Dev. 2009 Mar-Apr;126(3-4):270-7.

Dicer is regulated by cellular stresses and interferons.
Wiesen JL, Tomasi TB.
Mol Immunol. 2009 Mar;46(6):1222-8.

Signatures of purifying and local positive selection in human miRNAs.
Quach H, Barreiro LB, Laval G, Zidane N, Patin E, Kidd KK, Kidd JR, Bouchier C, Veuille M, Antoniewski C, Quintana-Murci L.
Am J Hum Genet. 2009 Mar;84(3):316-27.

Many roads to maturity: microRNA biogenesis pathways and their regulation.
Winter J, Jung S, Keller S, Gregory RI, Diederichs S.
Nat Cell Biol. 2009 Mar;11(3):228-34.

Uncoupling of lin-14 mRNA and protein repression by nutrient deprivation in Caenorhabditis elegans.
Holtz J, Pasquinelli AE.
RNA. 2009 Mar;15(3):400-5.

Phosphorylation of FMRP inhibits association with Dicer.
Cheever A, Ceman S.
RNA. 2009 Mar;15(3):362-6.

Transcriptional inhibiton of Hoxd4 expression by miRNA-10a in human breast cancer cells.
Tan Y, Zhang B, Wu T, Skogerbø G, Zhu X, Guo X, He S, Chen R.
BMC Mol Biol. 2009 Feb 22;10:12.

Selective stabilization of mammalian microRNAs by 3' adenylation mediated by the cytoplasmic poly(A) polymerase GLD-2.
Katoh T, Sakaguchi Y, Miyauchi K, Suzuki T, Kashiwabara S, Baba T, Suzuki T.
Genes Dev. 2009 Feb 15;23(4):433-8.

Recombination rates of human microRNA.
Zhao H, Wang D, Liu B, Jiang X, Zhang J, Fan M, Fan Z, Chen Y, Song SW, Gao W, Jiang T, Cui Q.
Biochem Biophys Res Commun. 2009 Feb 13;379(3):702-5.

Importin 8 is a gene silencing factor that targets argonaute proteins to distinct mRNAs.
Weinmann L, Höck J, Ivacevic T, Ohrt T, Mütze J, Schwille P, Kremmer E, Benes V, Urlaub H, Meister G.
Cell. 2009 Feb 6;136(3):496-507.

Aberrant epigenetic reprogramming of imprinted microRNA-127 and Rtl1 in cloned mouse embryos.
Cui XS, Zhang DX, Ko YG, Kim NH.
Biochem Biophys Res Commun. 2009 Feb 6;379(2):390-4.

Repression of C. elegans microRNA targets at the initiation level of translation requires GW182 proteins.
Ding XC, Grosshans H.
EMBO J. 2009 Feb 4;28(3):213-22.

Subnuclear compartmentalization of transiently expressed polyadenylated pri-microRNAs: processing at transcription sites or
accumulation in SC35 foci.
Pawlicki JM, Steitz JA.
Cell Cycle. 2009 Feb 1;8(3):345-56.

Essential and overlapping functions for mammalian Argonautes in microRNA silencing.
Su H, Trombly MI, Chen J, Wang X.
Genes Dev. 2009 Feb 1;23(3):304-17.

Stable Argonaute2 overexpression differentially regulates microRNA production.
Zhang X, Graves PR, Zeng Y.
Biochim Biophys Acta. 2009 Feb;1789(2):153-9.

Biological basis for restriction of microRNA targets to the 3' untranslated region in mammalian mRNAs.
Gu S, Jin L, Zhang F, Sarnow P, Kay MA.
Nat Struct Mol Biol. 2009 Feb;16(2):144-50.

A Drosophila pasha mutant distinguishes the canonical microRNA and mirtron pathways.
Martin R, Smibert P, Yalcin A, Tyler DM, Schäfer U, Tuschl T, Lai EC.
Mol Cell Biol. 2009 Feb;29(3):861-70.

A neomorphic sgs3 allele stabilizing miRNA cleavage products reveals that SGS3 acts as a homodimer.
Elmayan T, Adenot X, Gissot L, Lauressergues D, Gy I, Vaucheret H.
FEBS J. 2009 Feb;276(3):835-44.

The VEGF IRESes are differentially susceptible to translation inhibition by miR-16.
Karaa ZS, Iacovoni JS, Bastide A, Lacazette E, Touriol C, Prats H.
RNA. 2009 Feb;15(2):249-54.

Revisiting the principles of microRNA target recognition and mode of action.
Brodersen P, Voinnet O.
Nat Rev Mol Cell Biol. 2009 Feb;10(2):141-8.

Biogenesis of small RNAs in animals.
Kim VN, Han J, Siomi MC.
Nat Rev Mol Cell Biol. 2009 Feb;10(2):126-39.

Independent transcription of miR-281 in the intron of ODA in Drosophila melanogaster.
Xiong H, Qian J, He T, Li F.
Biochem Biophys Res Commun. 2009 Jan 23;378(4):883-9.

A three-dimensional view of the molecular machinery of RNA interference.
Jinek M, Doudna JA.
Nature. 2009 Jan 22;457(7228):405-12.

Transcriptional control of microRNA expression in C. elegans: promoting better understanding.
Turner MJ, Slack FJ.
RNA Biol. 2009 Jan-Mar;6(1):49-53.

The molecular machines that mediate microRNA maturation.
Lau PW, MacRae IJ.
J Cell Mol Med. 2009 Jan;13(1):54-60.

DNA methylomes, histone codes and miRNAs: tying it all together.
Guil S, Esteller M.
Int J Biochem Cell Biol. 2009 Jan;41(1):87-95.

Regulating the regulators: mechanisms controlling the maturation of microRNAs.
Ding XC, Weiler J, Grosshans H.
Trends Biotechnol. 2009 Jan;27(1):27-36.

Deadenylation is a widespread effect of miRNA regulation.
Eulalio A, Huntzinger E, Nishihara T, Rehwinkel J, Fauser M, Izaurralde E.
RNA. 2009 Jan;15(1):21-32.

Biochemical dissection of RISC assembly and function.
Tomari Y.
Nucleic Acids Symp Ser (Oxf). 2009;(53):15.

FANTOM4 EdgeExpressDB: an integrated database of promoters, genes, microRNAs, expression dynamics and regulatory interactions.
Severin J, Waterhouse AM, Kawaji H, Lassmann T, van Nimwegen E, Balwierz PJ, de Hoon MJ, Hume DA, Carninci P, Hayashizaki Y,
Suzuki H, Daub CO, Forrest AR.
Genome Biol. 2009;10(4):R39.

The FANTOM web resource: from mammalian transcriptional landscape to its dynamic regulation.
Kawaji H, Severin J, Lizio M, Waterhouse A, Katayama S, Irvine KM, Hume DA, Forrest AR, Suzuki H, Carninci P, Hayashizaki Y, Daub
CO.
Genome Biol. 2009;10(4):R40.

MicroRNA-biogenesis and Pre-mRNA splicing crosstalk.
Shomron N, Levy C.
J Biomed Biotechnol. 2009;2009:594678.

Studying alternative splicing regulatory networks through partial correlation analysis.
Chen L, Zheng S.
Genome Biol. 2009;10(1):R3.

Features of mammalian microRNA promoters emerge from polymerase II chromatin immunoprecipitation data.
Corcoran DL, Pandit KV, Gordon B, Bhattacharjee A, Kaminski N, Benos PV.
PLoS One. 2009;4(4):e5279.

Tissue and process specific microRNA-mRNA co-expression in mammalian development and malignancy.
Liu H, Kohane IS.
PLoS One. 2009;4(5):e5436.

Role of 3'UTRs in the translation of mRNAs regulated by oncogenic eIF4E--a computational inference.
Santhanam AN, Bindewald E, Rajasekhar VK, Larsson O, Sonenberg N, Colburn NH, Shapiro BA.
PLoS ONE. 2009;4(3):e4868.

The promoter of the pri-miR-375 gene directs expression selectively to the endocrine pancreas.
Avnit-Sagi T, Kantorovich L, Kredo-Russo S, Hornstein E, Walker MD.
PLoS ONE. 2009;4(4):e5033.

Protein components of the microRNA pathway and human diseases.
Perron MP, Provost P.
Methods Mol Biol. 2009;487:369-85.

Intron-mediated RNA interference and microRNA biogenesis.
Ying SY, Lin SL.
Methods Mol Biol. 2009;487:387-413.

MicroRNAs repress mainly through mRNA decay.
Esslinger S, Förstemann K.
Angew Chem Int Ed Engl. 2009;48(5):853-5.