Mechanism
RNA-binding protein Dnd1 inhibits microRNA access to target mRNA.
Kedde M, Strasser MJ, Boldajipour B, Vrielink JA, Slanchev K, le Sage C, Nagel R, Voorhoeve PM, van Duijse J, Ørom UA, Lund AH,
Perrakis A, Raz E, Agami R.
Cell. 2007 Dec 28;131(7):1273-86.
A dead end for microRNAs.
Ketting RF.
Cell. 2007 Dec 28;131(7):1226-7.
Switching from repression to activation: microRNAs can up-regulate translation.
Vasudevan S, Tong Y, Steitz JA.
Science. 2007 Dec 21;318(5858):1931-4.
Molecular biology. The two faces of miRNA.
Buchan JR, Parker R.
Science. 2007 Dec 21;318(5858):1877-8.
Dual role for argonautes in microRNA processing and posttranscriptional regulation of microRNA expression.
Diederichs S, Haber DA.
Cell. 2007 Dec 14;131(6):1097-108.
A whole-genome RNAi Screen for C. elegans miRNA pathway genes.
Parry DH, Xu J, Ruvkun G.
Curr Biol. 2007 Dec 4;17(23):2013-22.
Target-specific and global effectors in gene regulation by MicroRNA.
Levine E, Ben Jacob E, Levine H.
Biophys J. 2007 Dec 1;93(11):L52-4.
Dicer-1, but not Loquacious, is critical for assembly of miRNA-induced silencing complexes.
Liu X, Park JK, Jiang F, Liu Y, McKearin D, Liu Q.
RNA. 2007 Dec;13(12):2324-9.
Systematic evaluation of microRNA processing patterns in tissues, cell lines, and tumors.
Lee EJ, Baek M, Gusev Y, Brackett DJ, Nuovo GJ, Schmittgen TD.
RNA. 2007 Dec;14(1):35-42.
Systematic identification of C. elegans miRISC proteins, miRNAs, and mRNA targets by their interactions with GW182 proteins AIN-1 and
AIN-2.
Zhang L, Ding L, Cheung TH, Dong MQ, Chen J, Sewell AK, Liu X, Yates JR 3rd, Han M.
Mol Cell. 2007 Nov 30;28(4):598-613.
Derepression of microRNA-mediated protein translation inhibition by apolipoprotein B mRNA-editing enzyme catalytic polypeptide-like 3G
(APOBEC3G) and its family members.
Huang J, Liang Z, Yang B, Tian H, Ma J, Zhang H.
J Biol Chem. 2007 Nov 16;282(46):33632-40.
Lessons (not) learned from mistakes about translation.
Kozak M.
Gene. 2007 Nov 15;403(1-2):194-203.
P68 RNA helicase unwinds the human let-7 microRNA precursor duplex and is required for let-7-directed silencing of gene expression.
Salzman DW, Shubert-Coleman J, Furneaux H.
J Biol Chem. 2007 Nov 9;282(45):32773-9.
A small RNA regulates multiple ABC transporter mRNAs by targeting C/A-rich elements inside and upstream of ribosome-binding sites.
Sharma CM, Darfeuille F, Plantinga TH, Vogel J.
Genes Dev. 2007 Nov 1;21(21):2804-17.
The long and the short of RNA maps.
Ponjavic J, Ponting CP.
Bioessays. 2007 Nov;29(11):1077-80.
Proteomic and functional analysis of Argonaute-containing mRNA-protein complexes in human cells.
Höck J, Weinmann L, Ender C, Rüdel S, Kremmer E, Raabe M, Urlaub H, Meister G.
EMBO Rep. 2007 Nov;8(11):1052-60.
Determinants of targeting by endogenous and exogenous microRNAs and siRNAs.
Nielsen CB, Shomron N, Sandberg R, Hornstein E, Kitzman J, Burge CB.
RNA. 2007 Nov;13(11):1894-910.
Inter- and intra-combinatorial regulation by transcription factors and microRNAs.
Zhou Y, Ferguson J, Chang JT, Kluger Y.
BMC Genomics. 2007 Oct 30;8:396.
Target-specific requirements for enhancers of decapping in miRNA-mediated gene silencing.
Eulalio A, Rehwinkel J, Stricker M, Huntzinger E, Yang SF, Doerks T, Dorner S, Bork P, Boutros M, Izaurralde E.
Genes Dev. 2007 Oct 15;21(20):2558-70.
Target protectors reveal dampening and balancing of Nodal agonist and antagonist by miR-430.
Choi WY, Giraldez AJ, Schier AF.
Science. 2007 Oct 12;318(5848):271-4.
Effective RNAi-mediated gene silencing without interruption of the endogenous microRNA pathway.
John M, Constien R, Akinc A, Goldberg M, Moon YA, Spranger M, Hadwiger P, Soutschek J, Vornlocher HP, Manoharan M, Stoffel M,
Langer R, Anderson DG, Horton JD, Koteliansky V, Bumcrot D.
Nature. 2007 Oct 11;449(7163):745-7.
miRNAs play a tune.
Hobert O.
Cell. 2007 Oct 5;131(1):22-4.
miRNAs get an early start on translational silencing.
Meister G.
Cell. 2007 Oct 5;131(1):25-8.
A-to-I editing challenger or ally to the microRNA process.
Ohman M.
Biochimie. 2007 Oct;89(10):1171-6.
Structural features of small RNA precursors determine Argonaute loading in Caenorhabditis elegans.
Steiner FA, Hoogstrate SW, Okihara KL, Thijssen KL, Ketting RF, Plasterk RH, Sijen T.
Nat Struct Mol Biol. 2007 Oct;14(10):927-33.
The role of site accessibility in microRNA target recognition.
Kertesz M, Iovino N, Unnerstall U, Gaul U, Segal E.
Nat Genet. 2007 Oct;39(10):1278-84.
How microRNAs choose their targets.
Hofacker IL.
Nat Genet. 2007 Oct;39(10):1191-2.
A-to-I RNA editing: a new regulatory mechanism of global gene expression.
Amariglio N, Rechavi G.
Blood Cells Mol Dis. 2007 Sep-Oct;39(2):151-5.
Functional anatomy of the Drosophila microRNA-generating enzyme.
Ye X, Paroo Z, Liu Q.
J Biol Chem. 2007 Sep 28;282(39):28373-8.
Comparison of the contributions of the nuclear and cytoplasmic compartments to global gene expression in human cells.
Barthelson RA, Lambert GM, Vanier C, Lynch RM, Galbraith DW.
BMC Genomics. 2007 Sep 25;8:340.
MicroRNA inhibition of translation initiation in vitro by targeting the cap-binding complex eIF4F.
Mathonnet G, Fabian MR, Svitkin YV, Parsyan A, Huck L, Murata T, Biffo S, Merrick WC, Darzynkiewicz E, Pillai RS, Filipowicz W,
Duchaine TF, Sonenberg N.
Science. 2007 Sep 21;317(5845):1764-7.
Crystal structure of human DGCR8 core.
Sohn SY, Bae WJ, Kim JJ, Yeom KH, Kim VN, Cho Y.
Nat Struct Mol Biol. 2007 Sep;14(9):847-53.
Distinct ribonucleoprotein reservoirs for microRNA and siRNA populations in C. elegans.
Gu SG, Pak J, Barberan-Soler S, Ali M, Fire A, Zahler AM.
RNA. 2007 Sep;13(9):1492-504.
Global, comparative analysis of tissue-specific promoter CpG methylation.
Schilling E, Rehli M.
Genomics. 2007 Sep;90(3):314-23.
microRNAs: a safeguard against turmoil?
Leung AK, Sharp PA.
Cell. 2007 Aug 24;130(4):581-5.
MicroRNAs repress translation of m7Gppp-capped target mRNAs in vitro by inhibiting initiation and promoting deadenylation.
Standart N, Jackson RJ.
Genes Dev. 2007 Aug 15;21(16):1975-82.
Let-7 microRNA-mediated mRNA deadenylation and translational repression in a mammalian cell-free system.
Wakiyama M, Takimoto K, Ohara O, Yokoyama S.
Genes Dev. 2007 Aug 1;21(15):1857-62.
DNA methylation regulates MicroRNA expression.
Han L, Witmer PD, Casey E, Valle D, Sukumar S.
Cancer Biol Ther. 2007 Aug;6(8):1284-8.
Beginning to understand microRNA function.
Du T, Zamore PD.
Cell Res. 2007 Aug;17(8):661-3
RNA editing of the microRNA-151 precursor blocks cleavage by the Dicer-TRBP complex.
Kawahara Y, Zinshteyn B, Chendrimada TP, Shiekhattar R, Nishikura K.
EMBO Rep. 2007 Aug;8(8):763-9.
GW182 family proteins are crucial for microRNA-mediated gene silencing.
Ding L, Han M.
Trends Cell Biol. 2007 Aug;17(8):411-6.
Target mimicry provides a new mechanism for regulation of microRNA activity.
Franco-Zorrilla JM, Valli A, Todesco M, Mateos I, Puga MI, Rubio-Somoza I, Leyva A, Weigel D, Garcia JA, Paz-Ares J.
Nat Genet. 2007 Aug;39(8):1033-7.
A study of accessible motifs and RNA folding complexity.
Wexler Y, Zilberstein C, Ziv-Ukelson M.
J Comput Biol. 2007 Jul-Aug;14(6):856-72.
Drosophila microRNAs are sorted into functionally distinct argonaute complexes after production by dicer-1.
Forstemann K, Horwich MD, Wee L, Tomari Y, Zamore PD.
Cell. 2007 Jul 27;130(2):287-97.
The mirtron pathway generates microRNA-class regulatory RNAs in Drosophila.
Okamura K, Hagen JW, Duan H, Tyler DM, Lai EC.
Cell. 2007 Jul 13;130(1):89-100.
The role of microRNA in the delayed negative feedback regulation of gene expression.
Xie ZR, Yang HT, Liu WC, Hwang MJ.
Biochem Biophys Res Commun. 2007 Jul 6;358(3):722-6.
Intronic microRNA precursors that bypass Drosha processing.
Ruby JG, Jan CH, Bartel DP.
Nature. 2007 Jul 5;448(7149):83-6.
Pimet, the Drosophila homolog of HEN1, mediates 2'-O-methylation of Piwi- interacting RNAs at their 3' ends.
Saito K, Sakaguchi Y, Suzuki T, Suzuki T, Siomi H, Siomi MC.
Genes Dev. 2007 Jul 1;21(13):1603-8.
Cell to cell signalling via exosomes through esRNA.
Lotvall J, Valadi H.
Cell Adh Migr. 2007 Jul;1(3):156-8.
Global and local architecture of the mammalian microRNA-transcription factor regulatory network.
Shalgi R, Lieber D, Oren M, Pilpel Y.
PLoS Comput Biol. 2007 Jul;3(7):e131.
The multifunctional RNA-binding protein hnRNP A1 is required for processing of miR-18a.
Guil S, Caceres JF.
Nat Struct Mol Biol. 2007 Jul;14(7):591-6.
An mRNA m7G cap binding-like motif within human Ago2 represses translation.
Kiriakidou M, Tan GS, Lamprinaki S, De Planell-Saguer M, Nelson PT, Mourelatos Z.
Cell. 2007 Jun 15;129(6):1141-51.
MicroRNA silencing through RISC recruitment of eIF6.
Chendrimada TP, Finn KJ, Ji X, Baillat D, Gregory RI, Liebhaber SA, Pasquinelli AE, Shiekhattar R.
Nature. 2007 Jun 14;447(7146):823-8.
Drosophila miR2 induces pseudo-polysomes and inhibits translation initiation.
Thermann R, Hentze MW.
Nature. 2007 Jun 14;447(7146):875-8.
MicroRNA-mediated feedback and feedforward loops are recurrent network motifs in mammals.
Tsang J, Zhu J, van Oudenaarden A.
Mol Cell. 2007 Jun 8;26(5):753-67.
Argonaute proteins: mediators of RNA silencing.
Peters L, Meister G.
Mol Cell. 2007 Jun 8;26(5):611-23.
The coming of age for Piwi proteins.
Seto AG, Kingston RE, Lau NC.
Mol Cell. 2007 Jun 8;26(5):603-9.
Genome-wide mapping of in vivo protein-DNA interactions.
Johnson DS, Mortazavi A, Myers RM, Wold B.
Science. 2007 Jun 8;316(5830):1497-502.
Spatial preferences of microRNA targets in 3' untranslated regions.
Majoros WH, Ohler U.
BMC Genomics. 2007 Jun 7;8:152.
Target mRNAs are repressed as efficiently by microRNA-binding sites in the 5' UTR as in the 3' UTR.
Lytle JR, Yario TA, Steitz JA.
Proc Natl Acad Sci U S A. 2007 Jun 5;104(23):9667-72.
Origin and evolution of human microRNAs from transposable elements.
Piriyapongsa J, Marino-Ramirez L, Jordan IK.
Genetics. 2007 Jun;176(2):1323-37.
P-body formation is a consequence, not the cause, of RNA-mediated gene silencing.
Eulalio A, Behm-Ansmant I, Schweizer D, Izaurralde E.
Mol Cell Biol. 2007 Jun;27(11):3970-81.
Exosome-mediated transfer of mRNAs and microRNAs is a novel mechanism of genetic exchange between cells.
Valadi H, Ekstrom K, Bossios A, Sjostrand M, Lee JJ, Lotvall JO.
Nat Cell Biol. 2007 Jun;9(6):654-9.
Inheritance of an epigenetic change in the mouse: a new role for RNA.
Rassoulzadegan M, Grandjean V, Gounon P, Cuzin F.
Biochem Soc Trans. 2007 Jun;35(Pt 3):623-5.
Identification of specific sequence motifs in the upstream region of 242 human miRNA genes.
Inouchi A, Shinohara S, Inoue H, Kita K, Itakura M.
Comput Biol Chem. 2007 Jun;31(3):207-14.
The Caenorhabditis elegans pumilio homolog, puf-9, is required for the 3'UTR-mediated repression of the let-7 microRNA target gene,
hbl-1.
Nolde MJ, Saka N, Reinert KL, Slack FJ.
Dev Biol. 2007 May 15;305(2):551-63.
Mechanisms of microRNA-mediated gene regulation in animal cells.
Nilsen TW.
Trends Genet. 2007 May;23(5):243-9.
Epigenetics and microRNAs.
Chuang JC, Jones PA.
Pediatr Res. 2007 May;61(5 Pt 2):24R-29R.
Epigenetics and microRNAs.
Saetrom P, Snove O Jr, Rossi JJ.
Pediatr Res. 2007 May;61(5 Pt 2):17R-23R.
DEAD-box RNA helicase subunits of the Drosha complex are required for processing of rRNA and a subset of microRNAs.
Fukuda T, Yamagata K, Fujiyama S, Matsumoto T, Koshida I, Yoshimura K, Mihara M, Naitou M, Endoh H, Nakamura T, Akimoto C,
Yamamoto Y, Katagiri T, Foulds C, Takezawa S, Kitagawa H, Takeyama K, O'Malley BW, Kato S.
Nat Cell Biol. 2007 May;9(5):604-11.
Methylation of human microRNA genes in normal and neoplastic cells.
Weber B, Stresemann C, Brueckner B, Lyko F.
Cell Cycle. 2007 May;6(9):1001-5.
ADAR editing wobbles the microRNA world.
Das AK, Carmichael GG.
ACS Chem Biol. 2007 Apr 24;2(4):217-20.
Regulatory circuit of human microRNA biogenesis.
Lee J, Li Z, Brower-Sinning R, John B.
PLoS Comput Biol. 2007 Apr 20;3(4):e67.
The role of GW/P-bodies in RNA processing and silencing.
Jakymiw A, Pauley KM, Li S, Ikeda K, Lian S, Eystathioy T, Satoh M, Fritzler MJ, Chan EK.
J Cell Sci. 2007 Apr 15;120(Pt 8):1317-23.
Hypothesis: RNA editing of microRNA target sites in humans?
Liang H, Landweber LF.
RNA. 2007 Apr;13(4):463-7.
RNA stem-loops: to be or not to be cleaved by RNAse III.
Ritchie W, Legendre M, Gautheret D.
RNA. 2007 Apr;13(4):457-62.
Potent effect of target structure on microRNA function.
Long D, Lee R, Williams P, Chan CY, Ambros V, Ding Y.
Nat Struct Mol Biol. 2007 Apr;14(4):287-94.
Intronic microRNA: discovery and biological implications.
Li SC, Tang P, Lin WC.
DNA Cell Biol. 2007 Apr;26(4):195-207.
Argonautes and company: sailing against the wind.
Bhattacharyya SN, Filipowicz W.
Cell. 2007 Mar 23;128(6):1027-8.
miRNA editing--we should have inosine this coming.
Habig JW, Dale T, Bass BL.
Mol Cell. 2007 Mar 23;25(6):792-3.
Retained introns increase putative microRNA targets within 3' UTRs of human mRNA.
Tan S, Guo J, Huang Q, Chen X, Li-Ling J, Li Q, Ma F.
FEBS Lett. 2007 Mar 20;581(6):1081-6.
Evidence of spatially bound gene regulation in Mus musculus: decreased gene expression proximal to microRNA genomic location.
Inaoka H, Fukuoka Y, Kohane IS.
Proc Natl Acad Sci U S A. 2007 Mar 20;104(12):5020-5.
Characterization and identification of microRNA core promoters in four model species.
Zhou X, Ruan J, Wang G, Zhang W.
PLoS Comput Biol. 2007 Mar 9;3(3):e37.
Dynamic regulation of miRNA expression in ordered stages of cellular development.
Neilson JR, Zheng GX, Burge CB, Sharp PA.
Genes Dev. 2007 Mar 1;21(5):578-89.
Comparative evolutionary analysis of the FoxG1 transcription factor from diverse vertebrates identifies conserved recognition sites for
microRNA regulation.
Bredenkamp N, Seoighe C, Illing N.
Dev Genes Evol. 2007 Mar;217(3):227-33.
Repression of protein synthesis by miRNAs: how many mechanisms?
Pillai RS, Bhattacharyya SN, Filipowicz W.
Trends Cell Biol. 2007 Mar;17(3):118-26.
Transcripts targeted by the microRNA-16 family cooperatively regulate cell cycle progression.
Linsley PS, Schelter J, Burchard J, Kibukawa M, Martin MM, Bartz SR, Johnson JM, Cummins JM, Raymond CK, Dai H, Chau N, Cleary M,
Jackson AL, Carleton M, Lim L.
Mol Cell Biol. 2007 Mar;27(6):2240-52.
Biochemical mechanisms of the RNA-induced silencing complex.
Paroo Z, Liu Q, Wang X.
Cell Res. 2007 Mar;17(3):187-94.
Redirection of silencing targets by adenosine-to-inosine editing of miRNAs.
Kawahara Y, Zinshteyn B, Sethupathy P, Iizasa H, Hatzigeorgiou AG, Nishikura K.
Science. 2007 Feb 23;315(5815):1137-40.
Processing of intronic microRNAs.
Kim YK, Kim VN.
EMBO J. 2007 Feb 7;26(3):775-83.
Unique folding of precursor microRNAs: quantitative evidence and implications for de novo identification.
Ng Kwang Loong S, Mishra SK.
RNA. 2007 Feb;13(2):170-87.
Androgen responsive intronic non-coding RNAs.
Louro R, Nakaya HI, Amaral PP, Festa F, Sogayar MC, da Silva AM, Verjovski-Almeida S, Reis EM.
BMC Biol. 2007 Jan 30;5:4.
MicroRNAs preferentially target the genes with high transcriptional regulation complexity.
Cui Q, Yu Z, Pan Y, Purisima EO, Wang E.
Biochem Biophys Res Commun. 2007 Jan 19;352(3):733-8.
Distinct populations of primary and secondary effectors during RNAi in C. elegans.
Pak J, Fire A.
Science. 2007 Jan 12;315(5809):241-4.
A hexanucleotide element directs microRNA nuclear import.
Hwang HW, Wentzel EA, Mendell JT.
Science. 2007 Jan 5;315(5808):97-100.
How do microRNAs regulate gene expression?
Jackson RJ, Standart N.
Sci STKE. 2007 Jan 2;2007(367):re1.
Heme is involved in microRNA processing.
Faller M, Matsunaga M, Yin S, Loo JA, Guo F.
Nat Struct Mol Biol. 2007 Jan;14(1):23-9.
The chromatoid body: a germ-cell-specific RNA-processing centre.
Kotaja N, Sassone-Corsi P.
Nat Rev Mol Cell Biol. 2007 Jan;8(1):85-90.
[Ribosome recognizes aberrant translation termination and induces mRNA surveillance system]
Inada T.
Seikagaku. 2007 Jan;79(1):50-4.
Biological clocks and the coordination theory of RNA operons and regulons.
Keene JD.
Cold Spring Harb Symp Quant Biol. 2007;72:157-65.
The roles of binding site arrangement and combinatorial targeting in microRNA repression of gene expression.
Hon LS, Zhang Z.
Genome Biol. 2007;8(8):R166.
Tissue-dependent paired expression of miRNAs.
Ro S, Park C, Young D, Sanders KM, Yan W.
Nucleic Acids Res. 2007;35(17):5944-53.
Combinatorial delivery of small interfering RNAs reduces RNAi efficacy by selective incorporation into RISC.
Castanotto D, Sakurai K, Lingeman R, Li H, Shively L, Aagaard L, Soifer H, Gatignol A, Riggs A, Rossi JJ.
Nucleic Acids Res. 2007;35(15):5154-64.
Distance constraints between microRNA target sites dictate efficacy and cooperativity.
Saetrom P, Heale BS, Snove O Jr, Aagaard L, Alluin J, Rossi JJ.
Nucleic Acids Res. 2007;35(7):2333-42.
HEXIM1 is a promiscuous double-stranded RNA-binding protein and interacts with RNAs in addition to 7SK in cultured cells.
Li Q, Cooper JJ, Altwerger GH, Feldkamp MD, Shea MA, Price DH.
Nucleic Acids Res. 2007;35(8):2503-12.