Mechanism
The widespread impact of mammalian MicroRNAs on mRNA repression and evolution.
Farh KK, Grimson A, Jan C, Lewis BP, Johnston WK, Lim LP, Burge CB, Bartel DP.
Science. 2005 Dec 16;310(5755):1817-21.
Animal MicroRNAs confer robustness to gene expression and have a significant impact on 3'UTR evolution.
Stark A, Brennecke J, Bushati N, Russell RB, Cohen SM.
Cell. 2005 Dec 16;123(6):1133-46.
A human, ATP-independent, RISC assembly machine fueled by pre-miRNA.
Maniataki E, Mourelatos Z.
Genes Dev. 2005 Dec 15;19(24):2979-90.
Identification of novel argonaute-associated proteins.
Meister G, Landthaler M, Peters L, Chen PY, Urlaub H, Luhrmann R, Tuschl T.
Curr Biol. 2005 Dec 6;15(23):2149-55.
Slicer function of Drosophila Argonautes and its involvement in RISC formation.
Miyoshi K, Tsukumo H, Nagami T, Siomi H, Siomi MC.
Genes Dev. 2005 Dec 1;19(23):2837-48.
Regulating mammalian transcription with RNA.
Corey DR.
Trends Biochem Sci. 2005 Dec;30(12):655-8.
A role for the P-body component GW182 in microRNA function.
Liu J, Rivas FV, Wohlschlegel J, Yates JR 3rd, Parker R, Hannon GJ.
Nat Cell Biol. 2005 Dec;7(12):1261-6.
A novel C. elegans zinc finger transcription factor, lsy-2, required for the cell type-specific expression of the lsy-6 microRNA.
Johnston RJ Jr, Hobert O.
Development. 2005 Dec;132(24):5451-60.
MicroRNA function: multiple mechanisms for a tiny RNA?
Pillai RS.
RNA. 2005 Dec;11(12):1753-61.
MicroRNAs control translation initiation by inhibiting eukaryotic initiation factor 4E/cap and poly(A) tail function.
Humphreys DT, Westman BJ, Martin DI, Preiss T.
Proc Natl Acad Sci U S A. 2005 Nov 22;102(47):16961-6.
Passenger-strand cleavage facilitates assembly of siRNA into Ago2-containing RNAi enzyme complexes.
Matranga C, Tomari Y, Shin C, Bartel DP, Zamore PD.
Cell. 2005 Nov 18;123(4):607-20.
Human RISC couples microRNA biogenesis and posttranscriptional gene silencing.
Gregory RI, Chendrimada TP, Cooch N, Shiekhattar R.
Cell. 2005 Nov 18;123(4):631-40.
RNAi: RISC gets loaded.
Preall JB, Sontheimer EJ.
Cell. 2005 Nov 18;123(4):543-5.
Molecular biology. P-bodies mark the spot for controlling protein production.
Marx J.
Science. 2005 Nov 4;310(5749):764-5.
A crucial role for GW182 and the DCP1:DCP2 decapping complex in miRNA-mediated gene silencing.
Rehwinkel J, Behm-Ansmant I, Gatfield D, Izaurralde E.
RNA. 2005 Nov;11(11):1640-7.
microPrimer: the biogenesis and function of microRNA.
Du T, Zamore PD.
Development. 2005 Nov;132(21):4645-52.
Design of siRNAs producing unstructured guide-RNAs results in improved RNA interference efficiency.
Patzel V, Rutz S, Dietrich I, Koberle C, Scheffold A, Kaufmann SH.
Nat Biotechnol. 2005 Nov;23(11):1440-4.
Development of resistance to RNAi in mammalian cells.
Zheng ZM, Tang S, Tao M.
Ann N Y Acad Sci. 2005 Nov;1058:105-18.
Structural domains in RNAi.
Collins RE, Cheng X.
FEBS Lett. 2005 Oct 31;579(26):5841-9.
Small RNA asymmetry in RNAi: function in RISC assembly and gene regulation.
Hutvagner G.
FEBS Lett. 2005 Oct 31;579(26):5850-7.
Human microRNAs target a functionally distinct population of genes with AT-rich 3' UTRs.
Robins H, Press WH.
Proc Natl Acad Sci U S A. 2005 Oct 25;102(43):15557-62.
TRBP, a regulator of cellular PKR and HIV-1 virus expression, interacts with Dicer and functions in RNA silencing.
Haase AD, Jaskiewicz L, Zhang H, Laine S, Sack R, Gatignol A, Filipowicz W.
EMBO Rep. 2005 Oct;6(10):961-7.
MicroRNA: fine-tunes the function of genes in zebrafish.
Ying SY, Lin SL.
Biochem Biophys Res Commun. 2005 Sep 16;335(1):1-4.
MicroRNA-dependent trans-acting siRNA production.
Vaucheret H.
Sci STKE. 2005 Sep 6;2005(300):pe43.
Inhibition of translational initiation by Let-7 MicroRNA in human cells.
Pillai RS, Bhattacharyya SN, Artus CG, Zoller T, Cougot N, Basyuk E, Bertrand E, Filipowicz W.
Science. 2005 Sep 2;309(5740):1573-6.
Prediction of regulatory modules comprising microRNAs and target genes.
Yoon S, De Micheli G.
Bioinformatics. 2005 Sep 1;21 Suppl 2:ii93-100.
MicroRNA Mirn122a reduces expression of the posttranscriptionally regulated germ cell transition protein 2 (Tnp2) messenger RNA
(mRNA) by mRNA cleavage.
Yu Z, Raabe T, Hecht NB.
Biol Reprod. 2005 Sep;73(3):427-33.
Moments of the Boltzmann distribution for RNA secondary structures.
Miklos I, Meyer IM, Nagy B.
Bull Math Biol. 2005 Sep;67(5):1031-47.
Regulation by let-7 and lin-4 miRNAs results in target mRNA degradation.
Bagga S, Bracht J, Hunter S, Massirer K, Holtz J, Eachus R, Pasquinelli AE.
Cell. 2005 Aug 26;122(4):553-63.
The developmental timing regulator AIN-1 interacts with miRISCs and may target the argonaute protein ALG-1 to cytoplasmic P bodies in
C. elegans.
Ding L, Spencer A, Morita K, Han M.
Mol Cell. 2005 Aug 19;19(4):437-47.
Asymmetry of intronic pre-miRNA structures in functional RISC assembly.
Lin SL, Chang D, Ying SY.
Gene. 2005 Aug 15;356:32-8.
TRBP recruits the Dicer complex to Ago2 for microRNA processing and gene silencing.
Chendrimada TP, Gregory RI, Kumaraswamy E, Norman J, Cooch N, Nishikura K, Shiekhattar R.
Nature. 2005 Aug 4;436(7051):740-4.
Characterization of a highly variable eutherian microRNA gene.
Houbaviy HB, Dennis L, Jaenisch R, Sharp PA.
RNA. 2005 Aug;11(8):1245-57.
Efficient processing of primary microRNA hairpins by Drosha requires flanking nonstructured RNA sequences.
Zeng Y, Cullen BR.
J Biol Chem. 2005 Jul 29;280(30):27595-603.
Dicer-1 and R3D1-L catalyze microRNA maturation in Drosophila.
Jiang F, Ye X, Liu X, Fincher L, McKearin D, Liu Q.
Genes Dev. 2005 Jul 15;19(14):1674-9.
RNAi: the nuts and bolts of the RISC machine.
Filipowicz W.
Cell. 2005 Jul 15;122(1):17-20.
Processing of pre-microRNAs by the Dicer-1-Loquacious complex in Drosophila cells.
Saito K, Ishizuka A, Siomi H, Siomi MC.
PLoS Biol. 2005 Jul;3(7):e235.
Normal microRNA maturation and germ-line stem cell maintenance requires Loquacious, a double-stranded RNA-binding domain protein.
Forstemann K, Tomari Y, Du T, Vagin VV, Denli AM, Bratu DP, Klattenhoff C, Theurkauf WE, Zamore PD.
PLoS Biol. 2005 Jul;3(7):e236.
MicroRNA-dependent localization of targeted mRNAs to mammalian P-bodies.
Liu J, Valencia-Sanchez MA, Hannon GJ, Parker R.
Nat Cell Biol. 2005 Jul;7(7):719-23.
A potential link between transgene silencing and poly(A) tails.
Siomi MC, Tsukumo H, Ishizuka A, Nagami T, Siomi H.
RNA. 2005 Jul;11(7):1004-11.
RNAi and the P-body connection.
Rossi JJ.
Nat Cell Biol. 2005 Jul;7(7):643-4.
P-bodies take a RISC.
Jabri E.
Nat Struct Mol Biol. 2005 Jul;12(7):564.
MicroRNAs directing siRNA biogenesis.
Bartel B.
Nat Struct Mol Biol. 2005 Jul;12(7):569-71.
miRNAs: whys and wherefores of miRNA-mediated regulation.
Lai EC.
Curr Biol. 2005 Jun 21;15(12):R458-60.
Post-transcriptional gene silencing by siRNAs and miRNAs.
Filipowicz W, Jaskiewicz L, Kolb FA, Pillai RS.
Curr Opin Struct Biol. 2005 Jun;15(3):331-41.
MicroRNA biogenesis: coordinated cropping and dicing.
Kim VN.
Nat Rev Mol Cell Biol. 2005 May;6(5):376-85.
Genetic imprinting: conflict at the Callipyge locus.
Lewis A, Redrup L.
Curr Biol. 2005 Apr 26;15(8):R291-4.
RNAi-mediated allelic trans-interaction at the imprinted Rtl1/Peg11 locus.
Davis E, Caiment F, Tordoir X, Cavaille J, Ferguson-Smith A, Cockett N, Georges M, Charlier C.
Curr Biol. 2005 Apr 26;15(8):743-9.
Involvement of microRNA in AU-rich element-mediated mRNA instability.
Jing Q, Huang S, Guth S, Zarubin T, Motoyama A, Chen J, Di Padova F, Lin SC, Gram H, Han J.
Cell. 2005 Mar 11;120(5):623-34.
Microarray profiling of microRNAs reveals frequent coexpression with neighboring miRNAs and host genes.
Baskerville S, Bartel DP.
RNA. 2005 Mar;11(3):241-7.
Principles of microRNA-target recognition.
Brennecke J, Stark A, Russell RB, Cohen SM.
PLoS Biol. 2005 Mar;3(3):e85.
Comparative promoter region analysis powered by CORG.
Dieterich C, Grossmann S, Tanzer A, Ropcke S, Arndt PF, Stadler PF, Vingron M.
BMC Genomics. 2005 Feb 21;6(1):24.
Microarray analysis shows that some microRNAs downregulate large numbers of target mRNAs.
Lim LP, Lau NC, Garrett-Engele P, Grimson A, Schelter JM, Castle J, Bartel DP, Linsley PS, Johnson JM.
Nature. 2005 Feb 17;433(7027):769-73.
Cold stress-induced protein Rbm3 binds 60S ribosomal subunits, alters microRNA levels, and enhances global protein synthesis.
Dresios J, Aschrafi A, Owens GC, Vanderklish PW, Edelman GM, Mauro VP.
Proc Natl Acad Sci U S A. 2005 Feb 8;102(6):1865-70.
RNA interference: methylation mystery.
Ronemus M, Martienssen R.
Nature. 2005 Feb 3;433(7025):472-3.
Overexpression of exportin 5 enhances RNA interference mediated by short hairpin RNAs and microRNAs.
Yi R, Doehle BP, Qin Y, Macara IG, Cullen BR.
RNA. 2005 Feb;11(2):220-6.
Specific and potent RNAi in the nucleus of human cells.
Robb GB, Brown KM, Khurana J, Rana TM.
Nat Struct Mol Biol. 2005 Feb;12(2):133-7.
Mechanisms of translational control by the 3' UTR in development and differentiation.
de Moor CH, Meijer H, Lissenden S.
Semin Cell Dev Biol. 2005 Feb;16(1):49-58.
siRNA and miRNA: an insight into RISCs.
Tang G.
Trends Biochem Sci. 2005 Feb;30(2):106-14.
MicroRNA biogenesis: drosha can't cut it without a partner.
Tomari Y, Zamore PD.
Curr Biol. 2005 Jan 26;15(2):R61-4.
Intronic microRNAs.
Ying SY, Lin SL.
Biochem Biophys Res Commun. 2005 Jan 21;326(3):515-20.
Conserved seed pairing, often flanked by adenosines, indicates that thousands of human genes are microRNA targets.
Lewis BP, Burge CB, Bartel DP.
Cell. 2005 Jan 14;120(1):15-20.
Recognition and cleavage of primary microRNA precursors by the nuclear processing enzyme Drosha.
Zeng Y, Yi R, Cullen BR.
EMBO J. 2005 Jan 12;24(1):138-48.
Another view of the role of FMRP in translational regulation.
Zalfa F, Bagni C.
Cell Mol Life Sci. 2005 Jan;62(2):251-2.
As antisense RNA gets intronic.
Reis EM, Louro R, Nakaya HI, Verjovski-Almeida S.
OMICS. 2005 Spring;9(1):2-12.