Cancer

Genetic and epigenetic changes associated with cholangiocarcinoma: from DNA methylation to microRNAs.
Stutes M, Tran S, DeMorrow S.
World J Gastroenterol. 2007 Dec 28;13(48):6465-9.

MicroRNA-378 promotes cell survival, tumor growth, and angiogenesis by targeting SuFu and Fus-1 expression.
Lee DY, Deng Z, Wang CH, Yang BB.
Proc Natl Acad Sci U S A. 2007 Dec 18;104(51):20350-5.

Altered MicroRNA expression confined to specific epithelial cell subpopulations in breast cancer.
Sempere LF, Christensen M, Silahtaroglu A, Bak M, Heath CV, Schwartz G, Wells W, Kauppinen S, Cole CN.
Cancer Res. 2007 Dec 15;67(24):11612-20.

let-7 regulates self renewal and tumorigenicity of breast cancer cells.
Yu F, Yao H, Zhu P, Zhang X, Pan Q, Gong C, Huang Y, Hu X, Su F, Lieberman J, Song E.
Cell. 2007 Dec 14;131(6):1109-23.

An androgen-regulated miRNA suppresses Bak1 expression and induces androgen-independent growth of prostate cancer cells.
Shi XB, Xue L, Yang J, Ma AH, Zhao J, Xu M, Tepper CG, Evans CP, Kung HJ, deVere White RW.
Proc Natl Acad Sci U S A. 2007 Dec 11;104(50):19983-8.

MicroRNA expression signatures accurately discriminate acute lymphoblastic leukemia from acute myeloid leukemia.
Mi S, Lu J, Sun M, Li Z, Zhang H, Neilly MB, Wang Y, Qian Z, Jin J, Zhang Y, Bohlander SK, Le Beau MM, Larson RA, Golub TR, Rowley
JD, Chen J.
Proc Natl Acad Sci U S A. 2007 Dec 11;104(50):19971-6.

The guardian's little helper: microRNAs in the p53 tumor suppressor network.
He X, He L, Hannon GJ.
Cancer Res. 2007 Dec 1;67(23):11099-101.

MicroRNAs as potential agents to alter resistance to cytotoxic anticancer therapy.
Weidhaas JB, Babar I, Nallur SM, Trang P, Roush S, Boehm M, Gillespie E, Slack FJ.
Cancer Res. 2007 Dec 1;67(23):11111-6.

Inflammation and cancer: an ancient link with novel potentials.
Perwez Hussain S, Harris CC.
Int J Cancer. 2007 Dec 1;121(11):2373-80.

[MicroRNAs and cancer-associated signal transduction pathways]
Wu YY, Li LJ.
Yi Chuan. 2007 Dec;29(12):1419-28.

Murine models of chronic lymphocytic leukaemia: role of microRNA-16 in the New Zealand Black mouse model.
Scaglione BJ, Salerno E, Balan M, Coffman F, Landgraf P, Abbasi F, Kotenko S, Marti GE, Raveche ES.
Br J Haematol. 2007 Dec;139(5):645-57.

Chronic lymphocytic leukaemia genetics overview.
Caporaso N, Goldin L, Plass C, Calin G, Marti G, Bauer S, Raveche E, McMaster ML, Ng D, Landgren O, Slager S.
Br J Haematol. 2007 Dec;139(5):630-4.

MicroRNAs in the pathogeny of chronic lymphocytic leukaemia.
Nicoloso MS, Kipps TJ, Croce CM, Calin GA.
Br J Haematol. 2007 Dec;139(5):709-16.

MicroRNAs in tumorigenesis.
Skaftnesmo KO, Prestegarden L, Micklem DR, Lorens JB.
Curr Pharm Biotechnol. 2007 Dec;8(6):320-5.

let-7 microRNA expression is reduced in bronchioloalveolar carcinoma, a non-invasive carcinoma, and is not correlated with prognosis.
Inamura K, Togashi Y, Nomura K, Ninomiya H, Hiramatsu M, Satoh Y, Okumura S, Nakagawa K, Ishikawa Y.
Lung Cancer. 2007 Dec;58(3):392-6.

MicroRNA losses in the frequently deleted region of 7q in SMZL.
Ruiz-Ballesteros E, Mollejo M, Mateo M, Algara P, Martínez P, Piris MA.
Leukemia. 2007 Dec;21(12):2547-9.

Roles of microRNAs and their targets in cancer.
Stefani G.
Expert Opin Biol Ther. 2007 Dec;7(12):1833-40.

Specific microRNAs are downregulated in human thyroid anaplastic carcinomas.
Visone R, Pallante P, Vecchione A, Cirombella R, Ferracin M, Ferraro A, Volinia S, Coluzzi S, Leone V, Borbone E, Liu CG, Petrocca F,
Troncone G, Calin GA, Scarpa A, Colato C, Tallini G, Santoro M, Croce CM, Fusco A.
Oncogene. 2007 Nov 29;26(54):7590-5

microRNAs in viral oncogenesis.
Scaria V, Jadhav V.
Retrovirology. 2007 Nov 24;4:82.

Blockade of invasion and metastasis of breast cancer cells via targeting CXCR4 with an artificial microRNA.
Liang Z, Wu H, Reddy S, Zhu A, Wang S, Blevins D, Yoon Y, Zhang Y, Shim H.
Biochem Biophys Res Commun. 2007 Nov 23;363(3):542-6.

MicroRNAs found cavorting with p53.
Beckman M.
J Natl Cancer Inst. 2007 Nov 21;99(22):1664-5.

Genome-scale microRNA and small interfering RNA screens identify small RNA modulators of TRAIL-induced apoptosis pathway.
Ovcharenko D, Kelnar K, Johnson C, Leng N, Brown D.
Cancer Res. 2007 Nov 15;67(22):10782-8.

The oncogenic microRNA-27a targets genes that regulate specificity protein transcription factors and the G2-M checkpoint in
MDA-MB-231 breast cancer cells.
Mertens-Talcott SU, Chintharlapalli S, Li X, Safe S.
Cancer Res. 2007 Nov 15;67(22):11001-11.

Micro RNA 145 targets the insulin receptor substrate-1 and inhibits the growth of colon cancer cells.
Shi B, Sepp-Lorenzino L, Prisco M, Linsley P, deAngelis T, Baserga R.
J Biol Chem. 2007 Nov 9;282(45):32582-90.

Orthologous microRNA genes are located in cancer-associated genomic regions in human and mouse.
Makunin IV, Pheasant M, Simons C, Mattick JS.
PLoS ONE. 2007 Nov 7;2(11):e1133.

Computational analysis of biological functions and pathways collectively targeted by co-expressed microRNAs in cancer.
Gusev Y, Schmittgen TD, Lerner M, Postier R, Brackett D.
BMC Bioinformatics. 2007 Nov 1;8 Suppl 7:S16.

Hypermethylation of let-7a-3 in epithelial ovarian cancer is associated with low insulin-like growth factor-II expression and favorable
prognosis.
Lu L, Katsaros D, de la Longrais IA, Sochirca O, Yu H.
Cancer Res. 2007 Nov 1;67(21):10117-22.

miRNA expression profiles in chronic lymphocytic and acute lymphocytic leukemia.
Zanette DL, Rivadavia F, Molfetta GA, Barbuzano FG, Proto-Siqueira R, Silva-Jr WA, Falcão RP, Zago MA.
Braz J Med Biol Res. 2007 Nov;40(11):1435-40.

MicroRNA expression profiling in cancer from a bioinformatics prospective.
Gusev Y, Brackett DJ.
Expert Rev Mol Diagn. 2007 Nov;7(6):787-92.

Induction of cellular senescence by insulin-like growth factor binding protein-5 through a p53-dependent mechanism.
Kim KS, Seu YB, Baek SH, Kim MJ, Kim KJ, Kim JH, Kim JR.
Mol Biol Cell. 2007 Nov;18(11):4543-52.

p53 enters the microRNA world.
Hermeking H.
Cancer Cell. 2007 Nov;12(5):414-8.

Epigenetic silencing of the myelopoiesis regulator microRNA-223 by the AML1/ETO oncoprotein.
Fazi F, Racanicchi S, Zardo G, Starnes LM, Mancini M, Travaglini L, Diverio D, Ammatuna E, Cimino G, Lo-Coco F, Grignani F, Nervi C.
Cancer Cell. 2007 Nov;12(5):457-66.

High-throughput microRNAome analysis in human germ cell tumours.
Gillis AJ, Stoop HJ, Hersmus R, Oosterhuis JW, Sun Y, Chen C, Guenther S, Sherlock J, Veltman I, Baeten J, van der Spek PJ, de Alarcon
P, Looijenga LH.
J Pathol. 2007 Nov;213(3):319-28.

microRNAs join the p53 network--another piece in the tumour-suppression puzzle.
He L, He X, Lowe SW, Hannon GJ.
Nat Rev Cancer. 2007 Nov;7(11):819-22.

Transgenic over-expression of the microRNA miR-17-92 cluster promotes proliferation and inhibits differentiation of lung epithelial
progenitor cells.
Lu Y, Thomson JM, Wong HY, Hammond SM, Hogan BL.
Dev Biol. 2007 Oct 15;310(2):442-53.

MicroRNA let-7a down-regulates MYC and reverts MYC-induced growth in Burkitt lymphoma cells.
Sampson VB, Rong NH, Han J, Yang Q, Aris V, Soteropoulos P, Petrelli NJ, Dunn SP, Krueger LJ.
Cancer Res. 2007 Oct 15;67(20):9762-70.

Tumour invasion and metastasis initiated by microRNA-10b in breast cancer.
Ma L, Teruya-Feldstein J, Weinberg RA.
Nature. 2007 Oct 11;449(7163):682-8.

Cancer: micromanagement of metastasis.
Steeg PS.
Nature. 2007 Oct 11;449(7163):671-3.

Tumor protein 53-induced nuclear protein 1 expression is repressed by miR-155, and its restoration inhibits pancreatic tumor development.
Gironella M, Seux M, Xie MJ, Cano C, Tomasini R, Gommeaux J, Garcia S, Nowak J, Yeung ML, Jeang KT, Chaix A, Fazli L, Motoo Y,
Wang Q, Rocchi P, Russo A, Gleave M, Dagorn JC, Iovanna JL, Carrier A, Pébusque MJ, Dusetti NJ.
Proc Natl Acad Sci U S A. 2007 Oct 9;104(41):16170-5.

MicroRNA-29 family reverts aberrant methylation in lung cancer by targeting DNA methyltransferases 3A and 3B.
Fabbri M, Garzon R, Cimmino A, Liu Z, Zanesi N, Callegari E, Liu S, Alder H, Costinean S, Fernandez-Cymering C, Volinia S, Guler G,
Morrison CD, Chan KK, Marcucci G, Calin GA, Huebner K, Croce CM.
Proc Natl Acad Sci U S A. 2007 Oct 2;104(40):15805-10.

Retroviral insertional activation of the Fli-3 locus in erythroleukemias encoding a cluster of microRNAs that convert Epo-induced
differentiation to proliferation.
Cui JW, Li YJ, Sarkar A, Brown J, Tan YH, Premyslova M, Michaud C, Iscove N, Wang GJ, Ben-David Y.
Blood. 2007 Oct 1;110(7):2631-40.

MicroRNA-21 knockdown disrupts glioma growth in vivo and displays synergistic cytotoxicity with neural precursor cell delivered S-TRAIL
in human gliomas.
Corsten MF, Miranda R, Kasmieh R, Krichevsky AM, Weissleder R, Shah K.
Cancer Res. 2007 Oct 1;67(19):8994-9000.

[DNA sequencing of miR-17-92 cluster at chromosome 13q31-q32 in mantel cell lymphoma cell lines]
Xu W, Li JY, Shen QD, Li L, Yu H.
Zhongguo Shi Yan Xue Ye Xue Za Zhi. 2007 Oct;15(5):986-8.

Epigenetic regulation of protein-coding and microRNA genes by the Gfi1-interacting tumor suppressor PRDM5.
Duan Z, Person RE, Lee HH, Huang S, Donadieu J, Badolato R, Grimes HL, Papayannopoulou T, Horwitz MS.
Mol Cell Biol. 2007 Oct;27(19):6889-902.

MicroRNAs and cancer.
Cowland JB, Hother C, Grønbaek K.
APMIS. 2007 Oct;115(10):1090-106.

Micromanaging metastasis.
Schuldt A.
Nat Cell Biol. 2007 Oct;9(10):1121.

HMGA2 levels in CML: reflective of miRNA gene regulation in a hematopoietic tumor?
Godley LA.
Leuk Lymphoma. 2007 Oct;48(10):1898-9.

Micro-RNA profiling in kidney and bladder cancers.
Gottardo F, Liu CG, Ferracin M, Calin GA, Fassan M, Bassi P, Sevignani C, Byrne D, Negrini M, Pagano F, Gomella LG, Croce CM, Baffa
R.
Urol Oncol. 2007 Sep-Oct;25(5):387-92.

Detection of let-7a microRNA by real-time PCR in colorectal cancer: a single-centre experience from China.
Fang W, Lin C, Zhang H, Qian J, Zhong L, Xu N.
J Int Med Res. 2007 Sep-Oct;35(5):716-23.

OncomiRs: the discovery and progress of microRNAs in cancers.
Cho WC.
Mol Cancer. 2007 Sep 25;6:60.

Tumor-suppressive miR-34a induces senescence-like growth arrest through modulation of the E2F pathway in human colon cancer cells.
Tazawa H, Tsuchiya N, Izumiya M, Nakagama H.
Proc Natl Acad Sci U S A. 2007 Sep 25;104(39):15472-7.

The MUC1 and galectin-3 oncoproteins function in a microRNA-dependent regulatory loop.
Ramasamy S, Duraisamy S, Barbashov S, Kawano T, Kharbanda S, Kufe D.
Mol Cell. 2007 Sep 21;27(6):992-1004.

Prediction and preliminary validation of oncogene regulation by miRNAs.
Koscianska E, Baev V, Skreka K, Oikonomaki K, Rusinov V, Tabler M, Kalantidis K.
BMC Mol Biol. 2007 Sep 18;8:79.

MicroRNA-34b and MicroRNA-34c are targets of p53 and cooperate in control of cell proliferation and adhesion-independent growth.
Corney DC, Flesken-Nikitin A, Godwin AK, Wang W, Nikitin AY.
Cancer Res. 2007 Sep 15;67(18):8433-8.

MicroRNA signatures in human ovarian cancer.
Iorio MV, Visone R, Di Leva G, Donati V, Petrocca F, Casalini P, Taccioli C, Volinia S, Liu CG, Alder H, Calin GA, Ménard S, Croce CM.
Cancer Res. 2007 Sep 15;67(18):8699-707.

mir-29 regulates Mcl-1 protein expression and apoptosis.
Mott JL, Kobayashi S, Bronk SF, Gores GJ.
Oncogene. 2007 Sep 13;26(42):6133-40.

Apoptosis induction by antisense oligonucleotides against miR-17-5p and miR-20a in lung cancers overexpressing miR-17-92.
Matsubara H, Takeuchi T, Nishikawa E, Yanagisawa K, Hayashita Y, Ebi H, Yamada H, Suzuki M, Nagino M, Nimura Y, Osada H,
Takahashi T.
Oncogene. 2007 Sep 6;26(41):6099-105.

MicroRNA expression distinguishes between germinal center B cell-like and activated B cell-like subtypes of diffuse large B cell lymphoma.
Lawrie CH, Soneji S, Marafioti T, Cooper CD, Palazzo S, Paterson JC, Cattan H, Enver T, Mager R, Boultwood J, Wainscoat JS, Hatton
CS.
Int J Cancer. 2007 Sep 1;121(5):1156-61.

Overexpression of the microRNA hsa-miR-200c leads to reduced expression of transcription factor 8 and increased expression of
E-cadherin.
Hurteau GJ, Carlson JA, Spivack SD, Brock GJ.
Cancer Res. 2007 Sep 1;67(17):7972-6.

Progress on molecular markers of pancreatic cancer.
Grote T, Logsdon CD.
Curr Opin Gastroenterol. 2007 Sep;23(5):508-14.

MicroRNAs (miR)-221 and miR-222, both overexpressed in human thyroid papillary carcinomas, regulate p27Kip1 protein levels and cell
cycle.
Visone R, Russo L, Pallante P, De Martino I, Ferraro A, Leone V, Borbone E, Petrocca F, Alder H, Croce CM, Fusco A.
Endocr Relat Cancer. 2007 Sep;14(3):791-8.

MicroRNAs in tumorigenesis: a primer.
Zhang W, Dahlberg JE, Tam W.
Am J Pathol. 2007 Sep;171(3):728-38.

Modification of miR gene expression pattern in human colon cancer cells following exposure to 5-fluorouracil in vitro.
Rossi L, Bonmassar E, Faraoni I.
Pharmacol Res. 2007 Sep;56(3):248-53.

Ultraconserved regions encoding ncRNAs are altered in human leukemias and carcinomas.
Calin GA, Liu CG, Ferracin M, Hyslop T, Spizzo R, Sevignani C, Fabbri M, Cimmino A, Lee EJ, Wojcik SE, Shimizu M, Tili E, Rossi S,
Taccioli C, Pichiorri F, Liu X, Zupo S, Herlea V, Gramantieri L, Lanza G, Alder H, Rassenti L, Volinia S, Schmittgen TD, Kipps TJ, Negrini
M, Croce CM.
Cancer Cell. 2007 Sep;12(3):215-29.

The role of microRNA and other non-coding RNA in the pathogenesis of chronic lymphocytic leukemia.
Calin GA, Pekarsky Y, Croce CM.
Best Pract Res Clin Haematol. 2007 Sep;20(3):425-37.

Synergistic action of the microRNA-17 polycistron and Myc in aggressive cancer development.
Tagawa H, Karube K, Tsuzuki S, Ohshima K, Seto M.
Cancer Sci. 2007 Sep;98(9):1482-90.

Frequent loss of Dab2 protein and infrequent promoter hypermethylation in breast cancer.
Bagadi SA, Prasad CP, Srivastava A, Prashad R, Gupta SD, Ralhan R.
Breast Cancer Res Treat. 2007 Sep;104(3):277-86.

MicroRNA expression in lymphoma.
Lawrie CH.
Expert Opin Biol Ther. 2007 Sep;7(9):1363-74.

miRNA genetic alterations in human cancers.
Giannakakis A, Coukos G, Hatzigeorgiou A, Sandaltzopoulos R, Zhang L.
Expert Opin Biol Ther. 2007 Sep;7(9):1375-86.

Role of miRNA in carcinogenesis and biomarker selection: a methodological view.
Ahmed FE.
Expert Rev Mol Diagn. 2007 Sep;7(5):569-603.

"Myc'ed messages": myc induces transcription of E2F1 while inhibiting its translation via a microRNA polycistron.
Coller HA, Forman JJ, Legesse-Miller A.
PLoS Genet. 2007 Aug 31;3(8):e146.

mRNA/microRNA gene expression profile in microsatellite unstable colorectal cancer.
Lanza G, Ferracin M, Gafà R, Veronese A, Spizzo R, Pichiorri F, Liu CG, Calin GA, Croce CM, Negrini M.
Mol Cancer. 2007 Aug 23;6:54.

The let-7 microRNA represses cell proliferation pathways in human cells.
Johnson CD, Esquela-Kerscher A, Stefani G, Byrom M, Kelnar K, Ovcharenko D, Wilson M, Wang X, Shelton J, Shingara J, Chin L, Brown
D, Slack FJ.
Cancer Res. 2007 Aug 15;67(16):7713-22.

Interleukin-6 dependent survival of multiple myeloma cells involves the Stat3-mediated induction of microRNA-21 through a highly
conserved enhancer.
Loffler D, Brocke-Heidrich K, Pfeifer G, Stocsits C, Hackermuller J, Kretzschmar AK, Burger R, Gramatzki M, Blumert C, Bauer K, Cvijic H,
Ullmann AK, Stadler PF, Horn F.
Blood. 2007 Aug 15;110(4):1330-3.

Characterized mechanism of alpha-mangostin-induced cell death: caspase-independent apoptosis with release of endonuclease-G from
mitochondria and increased miR-143 expression in human colorectal cancer DLD-1 cells.
Nakagawa Y, Iinuma M, Naoe T, Nozawa Y, Akao Y.
Bioorg Med Chem. 2007 Aug 15;15(16):5620-8.

miR-221 and miR-222 expression affects the proliferation potential of human prostate carcinoma cell lines by targeting p27Kip1.
Galardi S, Mercatelli N, Giorda E, Massalini S, Frajese GV, Ciafre SA, Farace MG.
J Biol Chem. 2007 Aug 10;282(32):23716-24.

Regulation of the p27(Kip1) tumor suppressor by miR-221 and miR-222 promotes cancer cell proliferation.
le Sage C, Nagel R, Egan DA, Schrier M, Mesman E, Mangiola A, Anile C, Maira G, Mercatelli N, Ciafre SA, Farace MG, Agami R.
EMBO J. 2007 Aug 8;26(15):3699-708.

p53-mediated activation of miRNA34 candidate tumor-suppressor genes.
Bommer GT, Gerin I, Feng Y, Kaczorowski AJ, Kuick R, Love RE, Zhai Y, Giordano TJ, Qin ZS, Moore BB, MacDougald OA, Cho KR,
Fearon ER.
Curr Biol. 2007 Aug 7;17(15):1298-307.

Anti-oncomir suppression of tumor phenotypes.
Goga A, Benz C.
Mol Interv. 2007 Aug;7(4):199-202, 180.

Tiny actors, great roles: microRNAs in p53's service.
Raver-Shapira N, Oren M.
Cell Cycle. 2007 Aug;6(21):2656-61.

Let-7 prevents early cancer progression by suppressing expression of the embryonic gene HMGA2.
Park SM, Shell S, Radjabi AR, Schickel R, Feig C, Boyerinas B, Dinulescu DM, Lengyel E, Peter ME.
Cell Cycle. 2007 Aug;6(21):2585-90.

Testicular germ cell tumor susceptibility genes from the consomic 129.MOLF-Chr19 mouse strain.
Zhu R, Ji Y, Xiao L, Matin A.
Mamm Genome. 2007 Aug;18(8):584-95.

Analysis of gene expression in normal and neoplastic human testis: new roles of RNA.
Novotny GW, Nielsen JE, Sonne SB, Skakkebaek NE, Rajpert-De Meyts E, Leffers H.
Int J Androl. 2007 Aug;30(4):316-26; discussion 326-7.

Relevance of microRNAs in normal and malignant development, including human testicular germ cell tumours.
Looijenga LH, Gillis AJ, Stoop H, Hersmus R, Oosterhuis JW.
Int J Androl. 2007 Aug;30(4):304-14; discussion 314-5.

Chromosomal rearrangements and microRNAs: a new cancer link with clinical implications.
Calin GA, Croce CM.
J Clin Invest. 2007 Aug;117(8):2059-66.

Ras oncogenes and their downstream targets.
Rajalingam K, Schreck R, Rapp UR, Albert S.
Biochim Biophys Acta. 2007 Aug;1773(8):1177-95.

Global microRNA profiles in cervical squamous cell carcinoma depend on Drosha expression levels.
Muralidhar B, Goldstein LD, Ng G, Winder DM, Palmer RD, Gooding EL, Barbosa-Morais NL, Mukherjee G, Thorne NP, Roberts I, Pett
MR, Coleman N.
J Pathol. 2007 Aug;212(4):368-77.

MicroRNA-21 regulates expression of the PTEN tumor suppressor gene in human hepatocellular cancer.
Meng F, Henson R, Wehbe-Janek H, Ghoshal K, Jacob ST, Patel T.
Gastroenterology. 2007 Aug;133(2):647-58.

Identifying molecular markers for the early detection of pancreatic neoplasia.
Goggins M.
Semin Oncol. 2007 Aug;34(4):303-10.

AAV vector integration sites in mouse hepatocellular carcinoma.
Donsante A, Miller DG, Li Y, Vogler C, Brunt EM, Russell DW, Sands MS.
Science. 2007 Jul 27;317(5837):477.

MicroRNA-34a functions as a potential tumor suppressor by inducing apoptosis in neuroblastoma cells.
Welch C, Chen Y, Stallings RL.
Oncogene. 2007 Jul 26;26(34):5017-22.

Eukaryotic translation initiation factor 4E induced progression of primary human mammary epithelial cells along the cancer pathway is
associated with targeted translational deregulation of oncogenic drivers and inhibitors.
Larsson O, Li S, Issaenko OA, Avdulov S, Peterson M, Smith K, Bitterman PB, Polunovsky VA.
Cancer Res. 2007 Jul 15;67(14):6814-24.

Let-7 expression defines two differentiation stages of cancer.
Shell S, Park SM, Radjabi AR, Schickel R, Kistner EO, Jewell DA, Feig C, Lengyel E, Peter ME.
Proc Natl Acad Sci U S A. 2007 Jul 3;104(27):11400-5.

MicroRNA expression profiling in prostate cancer.
Porkka KP, Pfeiffer MJ, Waltering KK, Vessella RL, Tammela TL, Visakorpi T.
Cancer Res. 2007 Jul 1;67(13):6130-5.

Cyclin G1 is a target of miR-122a, a microRNA frequently down-regulated in human hepatocellular carcinoma.
Gramantieri L, Ferracin M, Fornari F, Veronese A, Sabbioni S, Liu CG, Calin GA, Giovannini C, Ferrazzi E, Grazi GL, Croce CM, Bolondi
L, Negrini M.
Cancer Res. 2007 Jul 1;67(13):6092-9.

Patterns of known and novel small RNAs in human cervical cancer.
Lui WO, Pourmand N, Patterson BK, Fire A.
Cancer Res. 2007 Jul 1;67(13):6031-43.

The role of microRNAs in cancer: no small matter.
Wiemer EA.
Eur J Cancer. 2007 Jul;43(10):1529-44.

Regulatory mechanisms of microRNAs involvement in cancer.
Fabbri M, Ivan M, Cimmino A, Negrini M, Calin GA.
Expert Opin Biol Ther. 2007 Jul;7(7):1009-19.

Differential regulation of microRNAs by p53 revealed by massively parallel sequencing: miR-34a is a p53 target that induces apoptosis
and G1-arrest.
Tarasov V, Jung P, Verdoodt B, Lodygin D, Epanchintsev A, Menssen A, Meister G, Hermeking H.
Cell Cycle. 2007 Jul;6(13):1586-93.

A microRNA component of the p53 tumour suppressor network.
He L, He X, Lim LP, de Stanchina E, Xuan Z, Liang Y, Xue W, Zender L, Magnus J, Ridzon D, Jackson AL, Linsley PS, Chen C, Lowe SW,
Cleary MA, Hannon GJ.
Nature. 2007 Jun 28;447(7148):1130-4.

MicroRNA expression alterations are linked to tumorigenesis and non-neoplastic processes in pancreatic ductal adenocarcinoma.
Szafranska AE, Davison TS, John J, Cannon T, Sipos B, Maghnouj A, Labourier E, Hahn SA.
Oncogene. 2007 Jun 28;26(30):4442-52.

Oncogenic All1 fusion proteins target Drosha-mediated microRNA processing.
Nakamura T, Canaani E, Croce CM.
Proc Natl Acad Sci U S A. 2007 Jun 26;104(26):10980-5.

MicroRNA expression profiles in head and neck cancer cell lines.
Tran N, McLean T, Zhang X, Zhao CJ, Thomson JM, O'Brien C, Rose B.
Biochem Biophys Res Commun. 2007 Jun 22;358(1):12-7.

[Relevance of microRNA-s in neoplastic diseases]
Tombol Z, Szabo P, Racz K, Tulassay Z, Igaz P.
Orv Hetil. 2007 Jun 17;148(24):1135-41.

CpG island hypermethylation of tumor suppressor microRNAs in human cancer.
Lujambio A, Esteller M.
Cell Cycle. 2007 Jun 15;6(12):1455-9.

Regulation of microRNA expression: the hypoxic component.
Kulshreshtha R, Ferracin M, Negrini M, Calin GA, Davuluri RV, Ivan M.
Cell Cycle. 2007 Jun 15;6(12):1426-31.

Oncogenic potential of the miR-106-363 cluster and its implication in human T-cell leukemia.
Landais S, Landry S, Legault P, Rassart E.
Cancer Res. 2007 Jun 15;67(12):5699-707.

Abnormal microRNA-16 locus with synteny to human 13q14 linked to CLL in NZB mice.
Raveche ES, Salerno E, Scaglione BJ, Manohar V, Abbasi F, Lin YC, Fredrickson T, Landgraf P, Ramachandra S, Huppi K, Toro JR,
Zenger VE, Metcalf RA, Marti GE.
Blood. 2007 Jun 15;109(12):5079-86.

MicroRNA gene expression during retinoic acid-induced differentiation of human acute promyelocytic leukemia.
Garzon R, Pichiorri F, Palumbo T, Visentini M, Aqeilan R, Cimmino A, Wang H, Sun H, Volinia S, Alder H, Calin GA, Liu CG, Andreeff M,
Croce CM.
Oncogene. 2007 Jun 14;26(28):4148-57.

Transactivation of miR-34a by p53 broadly influences gene expression and promotes apoptosis.
Chang TC, Wentzel EA, Kent OA, Ramachandran K, Mullendore M, Lee KH, Feldmann G, Yamakuchi M, Ferlito M, Lowenstein CJ, Arking
DE, Beer MA, Maitra A, Mendell JT.
Mol Cell. 2007 Jun 8;26(5):745-52.

Transcriptional activation of miR-34a contributes to p53-mediated apoptosis.
Raver-Shapira N, Marciano E, Meiri E, Spector Y, Rosenfeld N, Moskovits N, Bentwich Z, Oren M.
Mol Cell. 2007 Jun 8;26(5):731-43.

MicroRNA gene expression in malignant lymphoproliferative disorders.
Xu W, Li JY.
Chin Med J (Engl). 2007 Jun 5;120(11):996-9.

Retroviral insertional mutagenesis identifies genes that collaborate with NUP98-HOXD13 during leukemic transformation.
Slape C, Hartung H, Lin YW, Bies J, Wolff L, Aplan PD.
Cancer Res. 2007 Jun 1;67(11):5148-55.

MicroRNAs in human cancer: from research to therapy.
Negrini M, Ferracin M, Sabbioni S, Croce CM.
J Cell Sci. 2007 Jun 1;120(Pt 11):1833-40.

Quantitative technologies establish a novel microRNA profile of chronic lymphocytic leukemia.
Fulci V, Chiaretti S, Goldoni M, Azzalin G, Carucci N, Tavolaro S, Castellano L, Magrelli A, Citarella F, Messina M, Maggio R, Peragine N,
Santangelo S, Mauro FR, Landgraf P, Tuschl T, Weir DB, Chien M, Russo JJ, Ju J, Sheridan R, Sander C, Zavolan M, Guarini A, Foa R,
Macino G.
Blood. 2007 Jun 1;109(11):4944-51.

[Cloning and identification of microRNA from human osteosarcoma cell line SOSP-9607]
Gao J, Yang TT, Qiu XC, Yu B, Han JW, Fan QY, Ma BA.
Ai Zheng. 2007 Jun;26(6):561-5.

Estrogen-induced rat breast carcinogenesis is characterized by alterations in DNA methylation, histone modifications and aberrant
microRNA expression.
Kovalchuk O, Tryndyak VP, Montgomery B, Boyko A, Kutanzi K, Zemp F, Warbritton AR, Latendresse JR, Kovalchuk I, Beland FA,
Pogribny IP.
Cell Cycle. 2007 Jun;6(16):2010-8.

Regulation of p27Kip1 by miRNA 221/222 in glioblastoma.
Gillies JK, Lorimer IA.
Cell Cycle. 2007 Jun;6(16):2005-9.

Classifying microRNAs in cancer: the good, the bad and the ugly.
Voorhoeve PM, Agami R.
Biochim Biophys Acta. 2007 Jun;1775(2):274-82.

Peroxisome proliferator-activated receptor alpha regulates a microRNA-mediated signaling cascade responsible for hepatocellular
proliferation.
Shah YM, Morimura K, Yang Q, Tanabe T, Takagi M, Gonzalez FJ.
Mol Cell Biol. 2007 Jun;27(12):4238-47.

The 13q and 11q B-cell chronic lymphocytic leukaemia-associated regions derive from a common ancestral region in the zebrafish.
Auer RL, Riaz S, Cotter FE.
Br J Haematol. 2007 Jun;137(5):443-53.

Regulation of pri-microRNA BIC transcription and processing in Burkitt lymphoma.
Kluiver J, van den Berg A, de Jong D, Blokzijl T, Harms G, Bouwman E, Jacobs S, Poppema S, Kroesen BJ.
Oncogene. 2007 May 31;26(26):3769-76.

Post-transcriptional regulation of the Brn-3b transcription factor in differentiating neuroblastoma cells.
Calissano M, Diss JK, Latchman DS.
FEBS Lett. 2007 May 29;581(13):2490-6.

Detection of let-7a microRNA by real-time PCR in gastric carcinoma.
Zhang HH, Wang XJ, Li GX, Yang E, Yang NM.
World J Gastroenterol. 2007 May 28;13(20):2883-8.

Expression of the miR-17-92 polycistron in chronic myeloid leukemia (CML) CD34+ cells.
Venturini L, Battmer K, Castoldi M, Schultheis B, Hochhaus A, Muckenthaler MU, Ganser A, Eder M, Scherr M.
Blood. 2007 May 15;109(10):4399-405.

MicroRNA: Potential for Cancer Detection, Diagnosis, and Prognosis.
Tricoli JV, Jacobson JW.
Cancer Res. 2007 May 15;67(10):4553-5.

MicroRNA-21 targets the tumor suppressor gene tropomyosin 1 (TPM1).
Zhu S, Si ML, Wu H, Mo YY.
J Biol Chem. 2007 May 11;282(19):14328-36.

The interplay between microRNAs and the neurotrophin receptor tropomyosin-related kinase C controls proliferation of human
neuroblastoma cells.
Laneve P, Di Marcotullio L, Gioia U, Fiori ME, Ferretti E, Gulino A, Bozzoni I, Caffarelli E.
Proc Natl Acad Sci U S A. 2007 May 8;104(19):7957-62.

MicroRNA genes are frequently located near mouse cancer susceptibility loci.
Sevignani C, Calin GA, Nnadi SC, Shimizu M, Davuluri RV, Hyslop T, Demant P, Croce CM, Siracusa LD.
Proc Natl Acad Sci U S A. 2007 May 8;104(19):8017-22.

Translating MicroRNA discovery into clinical biomarkers in cancer.
Waldman SA, Terzic A.
JAMA. 2007 May 2;297(17):1923-5.

MicroRNA expression patterns to differentiate pancreatic adenocarcinoma from normal pancreas and chronic pancreatitis.
Bloomston M, Frankel WL, Petrocca F, Volinia S, Alder H, Hagan JP, Liu CG, Bhatt D, Taccioli C, Croce CM.
JAMA. 2007 May 2;297(17):1901-8.

Oncogenic HMGA2: short or small?
Young AR, Narita M.
Genes Dev. 2007 May 1;21(9):1005-9.

The tumor suppressor microRNA let-7 represses the HMGA2 oncogene.
Lee YS, Dutta A.
Genes Dev. 2007 May 1;21(9):1025-30.

Impaired microRNA processing enhances cellular transformation and tumorigenesis.
Kumar MS, Lu J, Mercer KL, Golub TR, Jacks T.
Nat Genet. 2007 May;39(5):673-7.

MicroRNAs as tumor suppressors.
Hammond SM.
Nat Genet. 2007 May;39(5):582-3.

The micro-ribonucleic acid (miRNA) miR-206 targets the human estrogen receptor-alpha (ERalpha) and represses ERalpha messenger
RNA and protein expression in breast cancer cell lines.
Adams BD, Furneaux H, White BA.
Mol Endocrinol. 2007 May;21(5):1132-47.

MicroRNA miR-181a correlates with morphological sub-class of acute myeloid leukaemia and the expression of its target genes in global
genome-wide analysis.
Debernardi S, Skoulakis S, Molloy G, Chaplin T, Dixon-McIver A, Young BD.
Leukemia. 2007 May;21(5):912-6.

MicroRNA expression profiles for the NCI-60 cancer cell panel.
Blower PE, Verducci JS, Lin S, Zhou J, Chung JH, Dai Z, Liu CG, Reinhold W, Lorenzi PL, Kaldjian EP, Croce CM, Weinstein JN, Sadee
W.
Mol Cancer Ther. 2007 May;6(5):1483-91.

MicroRNA-143 and -145 in colon cancer.
Akao Y, Nakagawa Y, Naoe T.
DNA Cell Biol. 2007 May;26(5):311-20.

MicroRNA and brain tumors: a cause and a cure?
Mathupala SP, Mittal S, Guthikonda M, Sloan AE.
DNA Cell Biol. 2007 May;26(5):301-10.

miRNA profiling for diagnosis and prognosis of human cancer.
Jay C, Nemunaitis J, Chen P, Fulgham P, Tong AW.
DNA Cell Biol. 2007 May;26(5):293-300.

Unique MicroRNA signature and clinical outcome of cancers.
Yu SL, Chen HY, Yang PC, Chen JJ.
DNA Cell Biol. 2007 May;26(5):283-92.

MicroRNAs as cancer players: potential clinical and biological effects.
Bandres E, Agirre X, Ramirez N, Zarate R, Garcia-Foncillas J.
DNA Cell Biol. 2007 May;26(5):273-82.

miR-21-mediated tumor growth.
Si ML, Zhu S, Wu H, Lu Z, Wu F, Mo YY.
Oncogene. 2007 Apr 26;26(19):2799-803.

Downregulation of CCR1 inhibits human hepatocellular carcinoma cell invasion.
Wu X, Fan J, Wang X, Zhou J, Qiu S, Yu Y, Liu Y, Tang Z.
Biochem Biophys Res Commun. 2007 Apr 20;355(4):866-71.

miRNAs in cancer: approaches, aetiology, diagnostics and therapy.
Blenkiron C, Miska EA.
Hum Mol Genet. 2007 Apr 15;16 Spec No 1:R106-13.

Epigenetic gene silencing in cancer: the DNA hypermethylome.
Esteller M.
Hum Mol Genet. 2007 Apr 15;16 Spec No 1:R50-9.

Translational repression of E2F1 mRNA in carcinoma in situ and normal testis correlates with expression of the miR-17-92 cluster.
Novotny GW, Sonne SB, Nielsen JE, Jonstrup SP, Hansen MA, Skakkebaek NE, Rajpert-De Meyts E, Kjems J, Leffers H.
Cell Death Differ. 2007 Apr;14(4):879-82.

A micro-RNA signature associated with race, tumor size, and target gene activity in human uterine leiomyomas.
Wang T, Zhang X, Obijuru L, Laser J, Aris V, Lee P, Mittal K, Soteropoulos P, Wei JJ.
Genes Chromosomes Cancer. 2007 Apr;46(4):336-47.

Disrupting the pairing between let-7 and Hmga2 enhances oncogenic transformation.
Mayr C, Hemann MT, Bartel DP.
Science. 2007 Mar 16;315(5818):1576-9.

The MicroRNA let-7a modulates interleukin-6-dependent STAT-3 survival signaling in malignant human cholangiocytes.
Meng F, Henson R, Wehbe-Janek H, Smith H, Ueno Y, Patel T.
J Biol Chem. 2007 Mar 16;282(11):8256-64.

Characterization of microRNA expression levels and their biological correlates in human cancer cell lines.
Gaur A, Jewell DA, Liang Y, Ridzon D, Moore JH, Chen C, Ambros VR, Israel MA.
Cancer Res. 2007 Mar 15;67(6):2456-68.

Effect of BRAFV600E mutation on transcription and post-transcriptional regulation in a papillary thyroid carcinoma model.
Cahill S, Smyth P, Denning K, Flavin R, Li J, Potratz A, Guenther SM, Henfrey R, O'Leary JJ, Sheils O.
Mol Cancer. 2007 Mar 13;6:21.

MicroRNAs linked to pancreatic cancer.
Hampton T.
JAMA. 2007 Mar 7;297(9):937.  

Expression profiling identifies microRNA signature in pancreatic cancer.
Lee EJ, Gusev Y, Jiang J, Nuovo GJ, Lerner MR, Frankel WL, Morgan DL, Postier RG, Brackett DJ, Schmittgen TD.
Int J Cancer. 2007 Mar 1;120(5):1046-54.

MicroRNA and cancer: Current status and prospective.
Wu W, Sun M, Zou GM, Chen J.
Int J Cancer. 2007 Mar 1;120(5):953-60.

microRNAs and cancer: role in tumorigenesis, patient classification and therapy.
Hernando E.
Clin Transl Oncol. 2007 Mar;9(3):155-60.

The human let-7a-3 locus contains an epigenetically regulated microRNA gene with oncogenic function.
Brueckner B, Stresemann C, Kuner R, Mund C, Musch T, Meister M, Sultmann H, Lyko F.
Cancer Res. 2007 Feb 15;67(4):1419-23.

Genetic unmasking of an epigenetically silenced microRNA in human cancer cells.
Lujambio A, Ropero S, Ballestar E, Fraga MF, Cerrato C, Setien F, Casado S, Suarez-Gauthier A, Sanchez-Cespedes M, Git A, Spiteri I,
Das PP, Caldas C, Miska E, Esteller M.
Cancer Res. 2007 Feb 15;67(4):1424-9.

microRNAs as oncogenes and tumor suppressors.
Zhang B, Pan X, Cobb GP, Anderson TA.
Dev Biol. 2007 Feb 1;302(1):1-12.

Differential patterns of microRNA expression in neuroblastoma are correlated with prognosis, differentiation, and apoptosis.
Chen Y, Stallings RL.
Cancer Res. 2007 Feb 1;67(3):976-83.

Identification of differentially expressed microRNAs by microarray: a possible role for microRNA genes in pituitary adenomas.
Bottoni A, Zatelli MC, Ferracin M, Tagliati F, Piccin D, Vignali C, Calin GA, Negrini M, Croce CM, Degli Uberti EC.
J Cell Physiol. 2007 Feb;210(2):370-7.

MicroRNAs and genomic instability.
Huppi K, Volfovsky N, Mackiewicz M, Runfola T, Jones TL, Martin SE, Stephens R, Caplen NJ.
Semin Cancer Biol. 2007 Feb;17(1):65-73.

Concomitant MYC and microRNA cluster miR-17-92 (C13orf25) amplification in human mantle cell lymphoma.
Rinaldi A, Poretti G, Kwee I, Zucca E, Catapano CV, Tibiletti MG, Bertoni F.
Leuk Lymphoma. 2007 Feb;48(2):410-2.

Impact of tiny miRNAs on cancers.
Liu W, Mao SY, Zhu WY.
World J Gastroenterol. 2007 Jan 28;13(4):497-502.

An E2F/miR-20a autoregulatory feedback loop.
Sylvestre Y, De Guire V, Querido E, Mukhopadhyay UK, Bourdeau V, Major F, Ferbeyre G, Chartrand P.
J Biol Chem. 2007 Jan 26;282(4):2135-43.

Direct regulation of an oncogenic micro-RNA cluster by E2F transcription factors.
Woods K, Thomson JM, Hammond SM.
J Biol Chem. 2007 Jan 26;282(4):2130-4.

Retroviral activation of the mir-106a microRNA cistron in T lymphoma.
Lum AM, Wang BB, Li L, Channa N, Bartha G, Wabl M.
Retrovirology. 2007 Jan 25;4:5.

High mobility group A2 is a target for miRNA-98 in head and neck squamous cell carcinoma.
Hebert C, Norris K, Scheper MA, Nikitakis N, Sauk JJ.
Mol Cancer. 2007 Jan 14;6:5.

Correlated break at PARK2/FRA6E and loss of AF-6/Afadin protein expression are associated with poor outcome in breast cancer.
Letessier A, Garrido-Urbani S, Ginestier C, Fournier G, Esterni B, Monville F, Adelaide J, Geneix J, Xerri L, Dubreuil P, Viens P,
Charafe-Jauffret E, Jacquemier J, Birnbaum D, Lopez M, Chaffanet M.
Oncogene. 2007 Jan 11;26(2):298-307.

Role for amplification and expression of glypican-5 in rhabdomyosarcoma.
Williamson D, Selfe J, Gordon T, Lu YJ, Pritchard-Jones K, Murai K, Jones P, Workman P, Shipley J.
Cancer Res. 2007 Jan 1;67(1):57-65.

MicroRNAs in biological processes and carcinogenesis.
Osada H, Takahashi T.
Carcinogenesis. 2007 Jan;28(1):2-12.

MicroRNAs and cancer.
Wijnhoven BP, Michael MZ, Watson DI.
Br J Surg. 2007 Jan;94(1):23-30.

Differential expression of miRNAs in papillary thyroid carcinoma compared to multinodular goiter using formalin fixed paraffin embedded
tissues.
Tetzlaff MT, Liu A, Xu X, Master SR, Baldwin DA, Tobias JW, Livolsi VA, Baloch ZW.
Endocr Pathol. 2007 Fall;18(3):163-73.

MicroRNA expression profiling of human breast cancer identifies new markers of tumor subtype.
Blenkiron C, Goldstein LD, Thorne NP, Spiteri I, Chin SF, Dunning MJ, Barbosa-Morais NL, Teschendorff AE, Green AR, Ellis IO, Tavaré
S, Caldas C, Miska EA.
Genome Biol. 2007;8(10):R214.

Investigation of microRNA alterations in leukemias and lymphomas.
Calin GA, Croce CM.
Methods Enzymol. 2007;427:193-213.

[Epigenetic inactivation of microRNA genes in mammary carcinoma]
Lehmann U, Hasemeier B, Römermann D, Müller M, Länger F, Kreipe H.
Verh Dtsch Ges Pathol. 2007;91:214-20.

Identification of the functional role of peroxiredoxin 6 in the progression of breast cancer.
Chang XZ, Li DQ, Hou YF, Wu J, Lu JS, Di GH, Jin W, Ou ZL, Shen ZZ, Shao ZM.
Breast Cancer Res. 2007;9(6):R76.

Altered expression of miR-21, miR-31, miR-143 and miR-145 is related to clinicopathologic features of colorectal cancer.
Slaby O, Svoboda M, Fabian P, Smerdova T, Knoflickova D, Bednarikova M, Nenutil R, Vyzula R.
Oncology. 2007;72(5-6):397-402.

MicroRNAs in carcinogenesis.
Hagan JP, Croce CM.
Cytogenet Genome Res. 2007;118(2-4):252-9.

Emerging role for microRNAs in acute promyelocytic leukemia.
Nervi C, Fazi F, Rosa A, Fatica A, Bozzoni I.
Curr Top Microbiol Immunol. 2007;313:73-84.

miRNAs in the biology of cancers and viral infections.
Yeung ML, Bennasser Y, Jeang KT.
Curr Med Chem. 2007;14(2):191-7.

A genetic screen implicates miRNA-372 and miRNA-373 as oncogenes in testicular germ cell tumors.
Voorhoeve PM, le Sage C, Schrier M, Gillis AJ, Stoop H, Nagel R, Liu YP, van Duijse J, Drost J, Griekspoor A, Zlotorynski E, Yabuta N, De
Vita G, Nojima H, Looijenga LH, Agami R.
Adv Exp Med Biol. 2007;604:17-46.

In silico analysis of p53 using the p53 knowledgebase: mutations, polymorphisms, microRNAs and pathways.
Yang Y, Tantoso E, Chua GH, Yeo ZX, Ng FS, Wong ST, Chung CW, Li KB.
In Silico Biol. 2007;7(1):61-75.