March 2010


Pharmacology

Stopping randomized trials early for benefit and estimation of treatment effects: systematic review and meta-regression analysis.
Bassler D, Briel M, Montori VM, Lane M, Glasziou P, Zhou Q, Heels-Ansdell D, Walter SD, Guyatt GH; STOPIT-2 Study Group, Flynn DN, Elamin MB, Murad MH, Abu Elnour NO, Lampropulos JF, Sood
A, Mullan RJ, Erwin PJ, Bankhead CR, Perera R, Ruiz Culebro C, You JJ, Mulla SM, Kaur J, Nerenberg KA, Schünemann H, Cook DJ, Lutz K, Ribic CM, Vale N, Malaga G, Akl EA, Ferreira-Gonzalez I,
Alonso-Coello P, Urrutia G, Kunz R, Bucher HC, Nordmann AJ, Raatz H, da Silva SA, Tuche F, Strahm B, Djulbegovic B, Adhikari NK, Mills EJ, Gwadry-Sridhar F, Kirpalani H, Soares HP, Karanicolas
PJ, Burns KE, Vandvik PO, Coto-Yglesias F, Chrispim PP, Ramsay T.
JAMA. 2010 Mar 24;303(12):1180-7.


Biology

Evidence of RNAi in humans from systemically administered siRNA via targeted nanoparticles.
Davis ME, Zuckerman JE, Choi CH, Seligson D, Tolcher A, Alabi CA, Yen Y, Heidel JD, Ribas A.
Nature. 2010 Mar 21.


("Science"[Jour] OR "Nature"[Jour] OR "The New England journal of medicine"[Jour] OR "JAMA : the journal of the American Medical Association"[Jour] OR "Archives of general psychiatry"[Jour] OR
"The American journal of psychiatry"[Jour] OR "Molecular psychiatry"[Jour] OR "Biological psychiatry"[Jour] OR "Neuron"[Jour] OR "Cell"[Jour] OR "Nature neuroscience"[Jour] OR "Nature genetics"[Jour]
OR "Proceedings of the National Academy of Sciences of the United States of America"[Jour] OR "The Journal of neuroscience : the official journal of the Society for Neuroscience"[Jour] OR "Nature
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