March 2007
Autism
Strong Association of De Novo Copy Number Mutations with Autism.
Sebat J, Lakshmi B, Malhotra D, Troge J, Lese-Martin C, Walsh T, Yamrom B, Yamrom B, Yoon S, Krasnitz A, Kendall J, Leotta A, Pai D, Zhang
R, Lee YH, Hicks J, Spence SJ, Lee AT, Puura K, Lehtimaki T, Ledbetter D, Gregersen PK, Bregman J, Sutcliffe JS, Jobanputra V, Chung W,
Warburton D, King MC, Skuse D, Geschwind DH, Gilliam TC, Ye K, Wigler M.
Science. 2007 Mar 15
Substance
Nucleus accumbens D2/3 receptors predict trait impulsivity and cocaine reinforcement.
Dalley JW, Fryer TD, Brichard L, Robinson ES, Theobald DE, Laane K, Pena Y, Murphy ER, Shah Y, Probst K, Abakumova I, Aigbirhio FI,
Richards HK, Hong Y, Baron JC, Everitt BJ, Robbins TW.
Science. 2007 Mar 2;315(5816):1267-70.
Schizophrenia
Effectiveness of Olanzapine, Quetiapine, and Risperidone in Patients With Chronic Schizophrenia After Discontinuing
Perphenazine: A CATIE Study.
Stroup TS, Lieberman JA, McEvoy JP, Swartz MS, Davis SM, Capuano GA, Rosenheck RA, Keefe RS, Miller AL, Belz I, Hsiao JK.
Am J Psychiatry. 2007 Mar;164(3):415-27.
Effects of Antipsychotic Medications on Psychosocial Functioning in Patients With Chronic Schizophrenia: Findings From the
NIMH CATIE Study.
Swartz MS, Perkins DO, Stroup TS, Davis SM, Capuano G, Rosenheck RA, Reimherr F, McGee MF, Keefe RS, McEvoy JP, Hsiao JK,
Lieberman JA.
Am J Psychiatry. 2007 Mar;164(3):428-36.
Depression
Patterns of gene expression in the limbic system of suicides with and without major depression.
Sequeira A, Klempan T, Canetti L, Ffrench-Mullen J, Benkelfat C, Rouleau GA, Turecki G.
Mol Psychiatry. 2007 Mar 13
Bipolar
Effectiveness of Adjunctive Antidepressant Treatment for Bipolar Depression.
Sachs GS, Nierenberg AA, Calabrese JR, Marangell LB, Wisniewski SR, Gyulai L, Friedman ES, Bowden CL, Fossey MD, Ostacher MJ, Ketter
TA, Patel J, Hauser P, Rapport D, Martinez JM, Allen MH, Miklowitz DJ, Otto MW, Dennehy EB, Thase ME.
N Engl J Med. 2007 Mar 28
Mania-like behavior induced by disruption of CLOCK.
Roybal K, Theobold D, Graham A, Dinieri JA, Russo SJ, Krishnan V, Chakravarty S, Peevey J, Oehrlein N, Birnbaum S, Vitaterna MH, Orsulak P,
Takahashi JS, Nestler EJ, Carlezon WA Jr, McClung CA.
Proc Natl Acad Sci U S A. 2007 Mar 22
Ethics
Pharmaceutical company payments to physicians: early experiences with disclosure laws in Vermont and Minnesota.
Ross JS, Lackner JE, Lurie P, Gross CP, Wolfe S, Krumholz HM.
JAMA. 2007 Mar 21;297(11):1216-23.
Psychology
Damage to the prefrontal cortex increases utilitarian moral judgements.
Koenigs M, Young L, Adolphs R, Tranel D, Cushman F, Hauser M, Damasio A.
Nature. 2007 Mar 21
Biology
Hyperconserved CpG domains underlie Polycomb-binding sites.
Tanay A, O'donnell AH, Damelin M, Bestor TH.
Proc Natl Acad Sci U S A. 2007 Mar 27;104(13):5521-6.
The implications of alternative splicing in the ENCODE protein complement.
Tress ML, Martelli PL, Frankish A, Reeves GA, Wesselink JJ, Yeats C, Olason PL, Albrecht M, Hegyi H, Giorgetti A, Raimondo D, Lagarde J,
Laskowski RA, Lopez G, Sadowski MI, Watson JD, Fariselli P, Rossi I, Nagy A, Kai W, Storling Z, Orsini M, Assenov Y, Blankenburg H,
Huthmacher C, Ramirez F, Schlicker A, Denoeud F, Jones P, Kerrien S, Orchard S, Antonarakis SE, Reymond A, Birney E, Brunak S, Casadio
R, Guigo R, Harrow J, Hermjakob H, Jones DT, Lengauer T, A Orengo C, Patthy L, Thornton JM, Tramontano A, Valencia A.
Proc Natl Acad Sci U S A. 2007 Mar 27;104(13):5495-500.
AU-Rich-Element-Mediated Upregulation of Translation by FXR1 and Argonaute 2.
Vasudevan S, Steitz JA.
Cell. 2007 Mar 23;128(6):1105-1118.
Control of Stress-Dependent Cardiac Growth and Gene Expression by a MicroRNA.
van Rooij E, Sutherland LB, Qi X, Richardson JA, Hill J, Olson EN.
Science. 2007 Mar 22
Evidence of spatially bound gene regulation in Mus musculus: Decreased gene expression proximal to microRNA genomic location.
Inaoka H, Fukuoka Y, Kohane IS.
Proc Natl Acad Sci U S A. 2007 Mar 20;104(12):5020-5.
Differential responses of hippocampal subfields to cortical up-down states.
Hahn TT, Sakmann B, Mehta MR.
Proc Natl Acad Sci U S A. 2007 Mar 20;104(12):5169-74.
Attention-like processes in Drosophila require short-term memory genes.
van Swinderen B.
Science. 2007 Mar 16;315(5818):1590-3.
Covalent modification of DNA regulates memory formation.
Miller CA, Sweatt JD.
Neuron. 2007 Mar 15;53(6):857-69.
Histone replacement marks the boundaries of cis-regulatory domains.
Mito Y, Henikoff JG, Henikoff S.
Science. 2007 Mar 9;315(5817):1408-11.
Discrete Small RNA-Generating Loci as Master Regulators of Transposon Activity in Drosophila.
Brennecke J, Aravin AA, Stark A, Dus M, Kellis M, Sachidanandam R, Hannon GJ.
Cell. 2007 Mar 7
Distribution, silencing potential and evolutionary impact of promoter DNA methylation in the human genome.
Weber M, Hellmann I, Stadler MB, Ramos L, Paabo S, Rebhan M, Schubeler D.
Nat Genet. 2007 Mar 4