January 2008


Substance

Genotype patterns that contribute to increased risk for or protection from developing heroin addiction.
Nielsen DA, Ji F, Yuferov V, Ho A, Chen A, Levran O, Ott J, Kreek MJ.
Mol Psychiatry. 2008 Jan 15


Schizophrenia

No Significant Association of 14 Candidate Genes With Schizophrenia in a Large European Ancestry Sample: Implications for Psychiatric Genetics.
Sanders AR, Duan J, Levinson DF, Shi J, He D, Hou C, Burrell GJ, Rice JP, Nertney DA, Olincy A, Rozic P, Vinogradov S, Buccola NG, Mowry BJ, Freedman R, Amin F, Black DW, Silverman JM,
Byerley WF, Crowe RR, Cloninger CR, Martinez M, Gejman PV.
Am J Psychiatry. 2008 Jan 15

Lifestyle intervention and metformin for treatment of antipsychotic-induced weight gain: a randomized controlled trial.
Wu RR, Zhao JP, Jin H, Shao P, Fang MS, Guo XF, He YQ, Liu YJ, Chen JD, Li LH.
JAMA. 2008 Jan 9;299(2):185-93.


Depression

Genetic architecture of the human tryptophan hydroxylase 2 Gene: existence of neural isoforms and relevance for major depression.
Haghighi F, Bach-Mizrachi H, Huang YY, Arango V, Shi S, Dwork AJ, Rosoklija G, Sheng HT, Morozova I, Ju J, Russo JJ, Mann JJ.
Mol Psychiatry. 2008 Jan 8

Elevated expression of tryptophan hydroxylase-2 mRNA at the neuronal level in the dorsal and median raphe nuclei of depressed suicides.
Bach-Mizrachi H, Underwood MD, Tin A, Ellis SP, Mann JJ, Arango V.
Mol Psychiatry. 2008 Jan 8

Elevated brain serotonin turnover in patients with depression: effect of genotype and therapy.
Barton DA, Esler MD, Dawood T, Lambert EA, Haikerwal D, Brenchley C, Socratous F, Hastings J, Guo L, Wiesner G, Kaye DM, Bayles R, Schlaich MP, Lambert GW.
Arch Gen Psychiatry. 2008 Jan;65(1):38-46.


Trauma

Mild traumatic brain injury in U.S. Soldiers returning from Iraq.
Hoge CW, McGurk D, Thomas JL, Cox AL, Engel CC, Castro CA.
N Engl J Med. 2008 Jan 31;358(5):453-63.

Trends in mental illness and suicidality after Hurricane Katrina.
Kessler RC, Galea S, Gruber MJ, Sampson NA, Ursano RJ, Wessely S.
Mol Psychiatry. 2008 Jan 8


Pharmacology

Selective publication of antidepressant trials and its influence on apparent efficacy.
Turner EH, Matthews AM, Linardatos E, Tell RA, Rosenthal R.
N Engl J Med. 2008 Jan 17;358(3):252-60.


Biology

Role of GSK3{beta} in behavioral abnormalities induced by serotonin deficiency.
Beaulieu JM, Zhang X, Rodriguiz RM, Sotnikova TD, Cools MJ, Wetsel WC, Gainetdinov RR, Caron MG.
Proc Natl Acad Sci U S A. 2008 Jan 22

Let Me Count the Ways: Mechanisms of Gene Regulation by miRNAs and siRNAs.
Wu L, Belasco JG.
Mol Cell. 2008 Jan 18;29(1):1-7.

A beta-arrestin 2 Signaling Complex Mediates Lithium Action on Behavior.
Beaulieu JM, Marion S, Rodriguiz RM, Medvedev IO, Sotnikova TD, Ghisi V, Wetsel WC, Lefkowitz RJ, Gainetdinov RR, Caron MG.
Cell. 2008 Jan 11;132(1):125-36.

Getting to the Root of miRNA-Mediated Gene Silencing.
Eulalio A, Huntzinger E, Izaurralde E.
Cell. 2008 Jan 11;132(1):9-14.