December 2006
ADHD
A polymorphism in the norepinephrine transporter gene alters promoter activity and is associated with attention-deficit
hyperactivity disorder.
Kim CH, Hahn MK, Joung Y, Anderson SL, Steele AH, Mazei-Robinson MS, Gizer I, Teicher MH, Cohen BM, Robertson D, Waldman ID, Blakely
RD, Kim KS.
Proc Natl Acad Sci U S A. 2006 Dec 4
Substance
Modulation of D2R-NR2B Interactions in Response to Cocaine.
Liu XY, Chu XP, Mao LM, Wang M, Lan HX, Li MH, Zhang GC, Parelkar NK, Fibuch EE, Haines M, Neve KA, Liu F, Xiong ZG, Wang JQ.
Neuron. 2006 Dec 7;52(5):897-909.
IRS2-Akt pathway in midbrain dopamine neurons regulates behavioral and cellular responses to opiates.
Russo SJ, Bolanos CA, Theobald DE, Decarolis NA, Renthal W, Kumar A, Winstanley CA, Renthal NE, Wiley MD, Self DW, Russell DS, Neve
RL, Eisch AJ, Nestler EJ.
Nat Neurosci. 2006 Dec 3
Schizophrenia
Cost-Effectiveness of Second-Generation Antipsychotics and Perphenazine in a Randomized Trial of Treatment for Chronic
Schizophrenia.
Rosenheck RA, Leslie DL, Sindelar J, Miller EA, Lin H, Stroup TS, McEvoy J, Davis SM, Keefe RS, Swartz M, Perkins DO, Hsiao JK, Lieberman
J.
Am J Psychiatry. 2006 Dec;163(12):2080-2089.
Randomized Comparison of Olanzapine Versus Risperidone for the Treatment of First-Episode Schizophrenia: 4-Month Outcomes.
Robinson DG, Woerner MG, Napolitano B, Patel RC, Sevy SM, Gunduz-Bruce H, Soto-Perello JM, Mendelowitz A, Khadivi A, Miller R,
McCormack J, Lorell BS, Lesser ML, Schooler NR, Kane JM.
Am J Psychiatry. 2006 Dec;163(12):2096-2102.
Depression
Meta-analysis of serotonin transporter gene promoter polymorphism (5-HTTLPR) association with selective serotonin reuptake
inhibitor efficacy in depressed patients.
Serretti A, Kato M, De Ronchi D, Kinoshita T.
Mol Psychiatry. 2006 Dec 5
Relationship Between Depression Severity Entry Criteria and Antidepressant Clinical Trial Outcomes.
Khan A, Schwartz K, Kolts RL, Ridgway D, Lineberry C.
Biol Psychiatry. 2006 Dec 1
Continuation Electroconvulsive Therapy vs Pharmacotherapy for Relapse Prevention in Major Depression: A Multisite Study From
the Consortium for Research in Electroconvulsive Therapy (CORE).
Kellner CH, Knapp RG, Petrides G, Rummans TA, Husain MM, Rasmussen K, Mueller M, Bernstein HJ, O'connor K, Smith G, Biggs M, Bailine
SH, Malur C, Yim E, McClintock S, Sampson S, Fink M.
Arch Gen Psychiatry. 2006 Dec;63(12):1337-44.
Postpartum
New parents and mental disorders: a population-based register study.
Munk-Olsen T, Laursen TM, Pedersen CB, Mors O, Mortensen PB.
JAMA. 2006 Dec 6;296(21):2582-9.
Suicide
Antidepressants and the risk of suicide, attempted suicide, and overall mortality in a nationwide cohort.
Tiihonen J, Lonnqvist J, Wahlbeck K, Klaukka T, Tanskanen A, Haukka J.
Arch Gen Psychiatry. 2006 Dec;63(12):1358-67.
Geriatrics
Long-term effects of cognitive training on everyday functional outcomes in older adults.
Willis SL, Tennstedt SL, Marsiske M, Ball K, Elias J, Koepke KM, Morris JN, Rebok GW, Unverzagt FW, Stoddard AM, Wright E; ACTIVE Study
Group.
JAMA. 2006 Dec 20;296(23):2805-14.
Biology
Human catechol-O-methyltransferase haplotypes modulate protein expression by altering mRNA secondary structure.
Nackley AG, Shabalina SA, Tchivileva IE, Satterfield K, Korchynskyi O, Makarov SS, Maixner W, Diatchenko L.
Science. 2006 Dec 22;314(5807):1930-3.
Ancient noncoding elements conserved in the human genome.
Venkatesh B, Kirkness EF, Loh YH, Halpern AL, Lee AP, Johnson J, Dandona N, Viswanathan LD, Tay A, Venter JC, Strausberg RL, Brenner S.
Science. 2006 Dec 22;314(5807):1892.
Genome-wide atlas of gene expression in the adult mouse brain.
Lein ES, Hawrylycz MJ, Ao N, Ayres M, Bensinger A, Bernard A, Boe AF, Boguski MS, Brockway KS, Byrnes EJ, Chen L, Chen L, Chen TM, Chi
Chin M, Chong J, Crook BE, Czaplinska A, Dang CN, Datta S, Dee NR, Desaki AL, Desta T, Diep E, Dolbeare TA, Donelan MJ, Dong HW,
Dougherty JG, Duncan BJ, Ebbert AJ, Eichele G, Estin LK, Faber C, Facer BA, Fields R, Fischer SR, Fliss TP, Frensley C, Gates SN, Glattfelder
KJ, Halverson KR, Hart MR, Hohmann JG, Howell MP, Jeung DP, Johnson RA, Karr PT, Kawal R, Kidney JM, Knapik RH, Kuan CL, Lake JH,
Laramee AR, Larsen KD, Lau C, Lemon TA, Liang AJ, Liu Y, Luong LT, Michaels J, Morgan JJ, Morgan RJ, Mortrud MT, Mosqueda NF, Ng LL,
Ng R, Orta GJ, Overly CC, Pak TH, Parry SE, Pathak SD, Pearson OC, Puchalski RB, Riley ZL, Rockett HR, Rowland SA, Royall JJ, Ruiz MJ,
Sarno NR, Schaffnit K, Shapovalova NV, Sivisay T, Slaughterbeck CR, Smith SC, Smith KA, Smith BI, Sodt AJ, Stewart NN, Stumpf KR, Sunkin
SM, Sutram M, Tam A, Teemer CD, Thaller C, Thompson CL, Varnam LR, Visel A, Whitlock RM, Wohnoutka PE, Wolkey CK, Wong VY, Wood
M, Yaylaoglu MB, Young RC, Youngstrom BL, Feng Yuan X, Zhang B, Zwingman TA, Jones AR.
Nature. 2006 Dec 6
Almost all human genes resulted from ancient duplication.
Britten RJ.
Proc Natl Acad Sci U S A. 2006 Dec 4
fruitless regulates aggression and dominance in Drosophila.
Vrontou E, Nilsen SP, Demir E, Kravitz EA, Dickson BJ.
Nat Neurosci. 2006 Dec;9(12):1469-71.