Current Research
Schizophrenia
A national study of violent behavior in persons
with schizophrenia.
Swanson JW, Swartz MS, Van Dorn RA, Elbogen EB,
Wagner HR, Rosenheck RA, Stroup TS, McEvoy JP,
Lieberman JA.
Arch Gen Psychiatry. 2006 May;63:490-9. PDF
Crime victimization in adults with severe mental illness:
comparison with the National Crime Victimization
Survey. Teplin LA, McClelland GM, Abram KM, Weiner DA.
Arch Gen Psychiatry. 2005 Aug;62:911-21. PDF
Geriatrics
The risk of suicide with selective serotonin
reuptake inhibitors in the elderly.
Juurlink DN, Mamdani MM, Kopp A, Redelmeier DA.
Am J Psychiatry. 2006 May;163:813-21. PDF
Antidepressants for depressed elderly. Mottram P, Wilson
K, Strobl J. Cochrane Database Syst Rev. 2006 Jan 25;
(1):CD003491.
Effectiveness of collaborative care for older
adults with Alzheimer disease in primary care: a
randomized controlled trial.
Callahan CM, Boustani MA, Unverzagt FW, Austrom
MG, Damush TM, Perkins AJ, Fultz BA, Hui SL,
Counsell SR, Hendrie HC.
JAMA. 2006 May 10;295:2148-57. PDF
Long term outcomes from the IMPACT randomised trial
for depressed elderly patients in primary care. Hunkeler
EM, Katon W, Tang L, Williams JW Jr, Kroenke K, Lin EH,
Harpole LH, Arean P, Levine S, Grypma LM, Hargreaves
WA, Unutzer J. BMJ. 2006 Feb 4;332:259-63. PDF
Depression and risk for Alzheimer disease:
systematic review, meta-analysis, and
metaregression analysis.
Ownby RL, Crocco E, Acevedo A, John V,
Loewenstein D.
Arch Gen Psychiatry. 2006 May;63:530-8. PDF
Depression as a risk factor for Alzheimer disease: the
MIRAGE Study. Green RC, Cupples LA, Kurz A, Auerbach
S, Go R, Sadovnick D, Duara R, Kukull WA, Chui H, Edeki
T, Griffith PA, Friedland RP, Bachman D, Farrer L. Arch
Neurol. 2003 May;60:753-9. PDF
Substance
Combined pharmacotherapies and behavioral
interventions for alcohol dependence: the
COMBINE study: a randomized controlled trial.
Anton RF, O'Malley SS, Ciraulo DA, Cisler RA, Couper
D, Donovan DM, Gastfriend DR, Hosking JD, Johnson
BA, LoCastro JS, Longabaugh R, Mason BJ, Mattson
ME, Miller WR, Pettinati HM, Randall CL, Swift R,
Weiss RD, Williams LD, Zweben A; COMBINE Study
Research Group.
JAMA. 2006 May 3;295:2003-17. PDF
Efficacy and tolerability of long-acting injectable
naltrexone for alcohol dependence: a randomized
controlled trial. Garbutt JC, Kranzler HR, O'Malley SS,
Gastfriend DR, Pettinati HM, Silverman BL, Loewy JW,
Ehrich EW; Vivitrex Study Group. JAMA. 2005 Apr 6;
293:1617-25. PDF
Depression
The thermolabile variant of MTHFR is associated
with depression in the British Women's Heart and
Health Study and a meta-analysis.
Lewis SJ, Lawlor DA, Davey Smith G, Araya R,
Timpson N, Day IN, Ebrahim S.
Mol Psychiatry. 2006 Apr;11:352-60. PDF
Homocysteine, methylenetetrahydrofolate reductase and
risk of schizophrenia: a meta-analysis. Muntjewerff JW,
Kahn RS, Blom HJ, den Heijer M. Mol Psychiatry. 2006 Feb;
11:143-9. PDF
Psychology
Neurobiological substrates of dread.
Berns GS, Chappelow J, Cekic M, Zink CF, Pagnoni
G, Martin-Skurski ME.
Science. 2006 May 5;312:754-8. PDF
Brain activity associated with expectancy-enhanced
placebo analgesia as measured by functional magnetic
resonance imaging. Kong J, Gollub RL, Rosman IS, Webb
JM, Vangel MG, Kirsch I, Kaptchuk TJ. J Neurosci. 2006
Jan 11;26:381-8. PDF
Pharmacology
Pharmaco-metabonomic phenotyping and
personalized drug treatment.
Clayton TA, Lindon JC, Cloarec O, Antti H, Charuel C,
Hanton G, Provost JP, Le Net JL, Baker D, Walley RJ,
Everett JR, Nicholson JK.
Nature. 2006 Apr 20;440:1073-7. PDF
Pharmacogenetics in drug regulation: promise, potential
and pitfalls. Shah RR. Philos Trans R Soc Lond B Biol Sci.
2005 Aug 29;360:1617-38. PDF
Biology
Reelin expression and glycosylation patterns are
altered in Alzheimer's disease.
Botella-Lopez A, Burgaya F, Gavin R, Garcia-Ayllon
MS, Gomez-Tortosa E, Pena-Casanova J, Urena JM,
Del Rio JA, Blesa R, Soriano E, Saez-Valero J.
Proc Natl Acad Sci U S A. 2006 Apr 4;103:5573-8.
PDF
CSF amyloid-beta-peptides in Alzheimer's disease,
dementia with Lewy bodies and Parkinson's disease
dementia. Bibl M, Mollenhauer B, Esselmann H, Lewczuk
P, Klafki HW, Sparbier K, Smirnov A, Cepek L, Trenkwalder
C, Ruther E, Kornhuber J, Otto M, Wiltfang J. Brain. 2006
May;129:1177-87. PDF
Adenosine A2a blockade prevents synergy
between mu-opiate and cannabinoid CB1
receptors and eliminates heroin-seeking behavior
in addicted rats.
Yao L, McFarland K, Fan P, Jiang Z, Ueda T, Diamond
I.
Proc Natl Acad Sci U S A. 2006 May 16;103:7877-82.
PDF
Activator of G protein signaling 3 regulates opiate
activation of protein kinase A signaling and relapse of
heroin-seeking behavior. Yao L, McFarland K, Fan P,
Jiang Z, Inoue Y, Diamond I. Proc Natl Acad Sci U S A.
2005 Jun 14;102:8746-51. PDF
Duke Research
Schizophrenia
A national study of violent behavior in persons
with schizophrenia.
Swanson JW, Swartz MS, Van Dorn RA, Elbogen EB,
Wagner HR, Rosenheck RA, Stroup TS, McEvoy JP,
Lieberman JA.
Arch Gen Psychiatry. 2006 May;63:490-9. PDF
Baseline Neurocognitive Deficits in the CATIE
Schizophrenia Trial.
Keefe RS, Bilder RM, Harvey PD, Davis SM, Palmer
BW, Gold JM, Meltzer HY, Green MF, Miller DD, Canive
JM, Adler LW, Manschreck TC, Swartz M, Rosenheck
R, Perkins DO, Walker TM, Stroup TS, McEvoy JP,
Lieberman JA.
Neuropsychopharmacology. 2006 Apr 19 PDF
Bipolar
Adjunctive risperidone, olanzapine and quetiapine
for the treatment of hospitalized patients with
bipolar I disorder: A retrospective study.
Pae CU, Nassir Ghaemi S, Patkar A, Chae JH, Bahk
WM, Jun TY, Masand P.
Prog Neuropsychopharmacol Biol Psychiatry. 2006 Apr
20 PDF
Geriatrics
Cognitive impairment and depression outcomes
in the IMPACT study.
Steffens DC, Snowden M, Fan MY, Hendrie H, Katon
WJ, Unutzer J; IMPACT Investigators.
Am J Geriatr Psychiatry. 2006 May;14:401-9. PDF
Mild Cognitive Impairment: Evaluation with 4-T
Functional MR Imaging.
Petrella JR, Krishnan S, Slavin MJ, Tran TT, Murty L,
Doraiswamy PM.
Radiology. 2006 May 9 Full Text
ADHD
Assessing medication effects in the MTA study
using neuropsychological outcomes.
Epstein JN, Conners CK, Hervey AS, Tonev ST, Arnold
LE, Abikoff HB, Elliott G, Greenhill LL, Hechtman L,
Hoagwood K, Hinshaw SP, Hoza B, Jensen PS, March
JS, Newcorn JH, Pelham WE, Severe JB, Swanson
JM, Wells K, Vitiello B, Wigal T; MTA Cooperative
Study Group.
J Child Psychol Psychiatry. 2006 May;47:446-56. Full
Text
Prevalence of DSM-IV-Defined Mood, Anxiety, and
Substance Use Disorders in an HIV Clinic in the
Southeastern United States.
Pence BW, Miller WC, Whetten K, Eron JJ, Gaynes BN.
J Acquir Immune Defic Syndr. 2006 Apr 24
Prevalence of Childhood Sexual Abuse and
Physical Trauma in a Southern HIV-Positive
Sample.
Whetten K, Leserman J, Lowe Geonnotti K, Stangl D,
Thielman N, Swartz M, Hanisch L, Van Scoyoc L.
Am J Public Health. 2006 May 2 PDF
Knowledge and risks of human
immunodeficiency virus transmission among
veterans with severe mental illness.
Strauss JL, Bosworth HB, Stechuchak KM, Meador
KM, Butterfield MI.
Mil Med. 2006 Apr;171:325-30.
Predicting negative mood state and personal
growth in african american and white long-term
breast cancer survivors.
Porter LS, Clayton MF, Belyea M, Mishel M, Gil KM,
Germino BB.
Ann Behav Med. 2006 Jun;31:195-204.
Transcerebral platelet activation after aortic
cross-clamp release is linked to neurocognitive
decline.
Mathew JP, Rinder HM, Smith BR, Newman MF,
Rinder CS.
Ann Thorac Surg. 2006 May;81:1644-9. PDF
Genetics
Embracing the complexity of genomic data for
personalized medicine.
West M, Ginsburg GS, Huang AT, Nevins JR.
Genome Res. 2006 May;16:559-66. PDF
Autism
Lack of Association Between Autism and
SLC25A12.
Rabionet R, McCauley Ph D JL, Jaworski M P H JM,
Ashley-Koch AE, Martin ER, Sutcliffe JS, Haines JL,
Delong GR, Abramson RK, Wright HH, Cuccaro ML,
Gilbert JR, Pericak-Vance MA.
Am J Psychiatry. 2006 May;163:929-31. PDF
An analysis paradigm for investigating multi-locus
effects in complex disease: examination of three
GABA receptor subunit genes on 15q11-q13 as
risk factors for autistic disorder.
Ashley-Koch AE, Mei H, Jaworski J, Ma DQ, Ritchie
MD, Menold MM, Delong GR, Abramson RK, Wright
HH, Hussman JP, Cuccaro ML, Gilbert JR, Martin ER,
Pericak-Vance MA.
Ann Hum Genet. 2006 May;70:281-92. Full Text
Sleep
Identifying critical beliefs about sleep in primary
insomnia.
Carney CE, Edinger JD.
Sleep. 2006 Apr 1;29:444-53.
Defining insomnia: quantitative criteria for
insomnia severity and frequency.
Lineberger MD, Carney CE, Edinger JD, Means MK.
Sleep. 2006 Apr 1;29:479-85.
Pain
Neurostimulation for the treatment of intractable
facial pain.
Osenbach R.
Pain Med. 2006 May-Jun;7 Suppl 1:S126-36. Full Text
Geographic Variation in the Prescription of
Schedule II Opioid Analgesics among Outpatients
in the United States.
Curtis LH, Stoddard J, Radeva JI, Hutchison S, Dans
PE, Wright A, Woosley RL, Schulman KA.
Health Serv Res. 2006 Jun;41:837-55. Full Text
Pharmacology
Initial experience with teriparatide in the United
States.
Gold DT, Pantos BS, Masica DN, Misurski DA, Marcus
R.
Curr Med Res Opin. 2006 Apr;22:703-8.
Transdermal selegiline: the new generation of
monoamine oxidase inhibitors.
Patkar AA, Pae CU, Masand PS.
CNS Spectr. 2006 May;11:363-75.
Therapy
Self-system therapy as an intervention for
self-regulatory dysfunction in depression: a
randomized comparison with cognitive therapy.
Strauman TJ, Vieth AZ, Merrill KA, Kolden GG, Woods
TE, Klein MH, Papadakis AA, Schneider KL, Kwapil L.
J Consult Clin Psychol. 2006 Apr;74:367-76.
Early alliance, alliance ruptures, and symptom
change in a nonrandomized trial of cognitive
therapy for avoidant and obsessive-compulsive
personality disorders.
Strauss JL, Hayes AM, Johnson SL, Newman CF,
Brown GK, Barber JP, Laurenceau JP, Beck AT.
J Consult Clin Psychol. 2006 Apr;74:337-45.
Substance
Differential effects of delta(9)-THC on learning in
adolescent and adult rats.
Cha YM, White AM, Kuhn CM, Wilson WA,
Swartzwelder HS.
Pharmacol Biochem Behav. 2006 Apr 20 PDF
Toxicology
Toxicogenomic Studies of the Rat Brain at an
Early Time Point Following Acute Sarin Exposure.
Damodaran TV, Greenfield ST, Patel AG, Dressman
HK, K Lin S, Abou-Donia MB.
Neurochem Res. 2006 May 13 PDF
Comparative developmental neurotoxicity of
organophosphate insecticides: effects on brain
development are separable from systemic toxicity.
Slotkin TA, Levin ED, Seidler FJ.
Environ Health Perspect. 2006 May;114:746-51. PDF
Chlorpyrifos affects phenotypic outcomes in a
model of mammalian neurodevelopment: critical
stages targeting differentiation in PC12 cells.
Jameson RR, Seidler FJ, Qiao D, Slotkin TA.
Environ Health Perspect. 2006 May;114:667-72. PDF
Psychology
The relation of free plasma tryptophan to anger,
hostility, and aggression in a nonpatient sample
of adult men and women.
Suarez EC, Krishnan KR.
Ann Behav Med. 2006 Jun;31:254-60.
Dissociation of event-related potentials indexing
arousal and semantic cohesion during emotional
word encoding.
Dillon DG, Cooper JJ, Grent-'t-Jong T, Woldorff MG,
Labar KS.
Brain Cogn. 2006 May 5 PDF
Retaining the meaning of the words religiousness
and spirituality: A commentary on the WHOQOL
SRPB group's "A cross-cultural study of
spirituality, religion, and personal beliefs as
components of quality of life" (62: 6, 2005,
1486-1497).
Moreira-Almeida A, Koenig HG.
Soc Sci Med. 2006 Apr 28 PDF
Low-dose mecamylamine improves learning of
rats in the radial-arm maze repeated acquisition
procedure.
Levin ED, Caldwell DP.
Neurobiol Learn Mem. 2006 Apr 21 PDF
Shared system for ordering small and large
numbers in monkeys and humans.
Cantlon JF, Brannon EM.
Psychol Sci. 2006 May;17:401-6. Full Text